This book brings together conceptual, theoretical, policy-based, and empirical contributions from multidisciplinary lenses to bridge the existing knowledge gap in the field of medicine, entrepreneurship and health economics. This book serves as a much needed intellectual resource providing guidance to the entrepreneurial-minded medical doctors (Medipreneurs), social entrepreneurs, policymakers, academics on the subject matter with a view of applying the knowledge gained for reinvigorating the healthcare delivery system leveraging a business approach. The contributions serve as a guide to connect entrepreneurially with market opportunities, especially to provide relevant health-oriented products, services, technologies and other medical solutions for social impact in the developed and developing countries with the overarching goal of assisting policymakers to accelerate the attainment of the Sustainable Development Goal 3 (SDG3).