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In compiling this textbook on the exciting novel imaging modality
of PET/MRI, the editors have brought together a truly international
group of experts in the field. The book is divided into two parts.
The first part covers methodology and equipment and includes
chapters on basic molecular medicine, contrast agents, MR
attenuation and validation, and quantitative MRI and PET motion
correction. The second part of the book focuses on clinical
applications in oncology, cardiology, and neurology. Imaging of
major neoplasms is covered in a series of individual chapters.
Further chapters address functional and metabolic cardiovascular
examinations and major central nervous system applications such as
brain tumors and dementias. This book will be of interest to all
radiologists and nuclear medicine physicians who wish to learn more
about the latest developments in this important emerging imaging
modality and its applications.
Heart transplantation remains one of the major scientific
achievements of twentieth century medicine. During the past four
decades, it has evolved from an unproven experimental surgical
technique to the most effective form of therapy for refractory
end-stage heart disease. It has captured the public's imagination
and expanded our understanding of fundamental immunologic
mechanisms that are responsible for cellular and humorally-mediated
immunity. Despite its successes, many clinical and scientific
problems remain. One or more bouts of acute cellular or humoral
(vascular) rejection will occur in over 75% of transplant
recipients despite current immunosuppressive strategies. Further,
rejection directly results in approximately 20% of post-transplant
deaths and is believed to play a major role in the development of
late allograft dysfunction and coronary vasculopathy. This book by
international experts in the fields of transplantation medicine,
immunobiology and cardiac imaging provides the reader with an
up-to-date, consise summary of the latest developments in the
diagnosis and treatment of acute cardiac rejection. It is axiomatic
that a more complete understanding of the pathogenic processes
involved in rejection will ultimately lead to its prevention. This
volume will be useful to transplant cardiologists, cardiovascular
surgeons, cardiac pathologists and transplant scientists who seek
to prolong the lifespan and improve the quality of life of their
transplant recipients.
Heart transplantation remains one of the major scientific
achievements of twentieth century medicine. During the past four
decades, it has evolved from an unproven experimental surgical
technique to the most effective form of therapy for refractory
end-stage heart disease. It has captured the public's imagination
and expanded our understanding of fundamental immunologic
mechanisms that are responsible for cellular and humorally-mediated
immunity. Despite its successes, many clinical and scientific
problems remain. One or more bouts of acute cellular or humoral
(vascular) rejection will occur in over 75% of transplant
recipients despite current immunosuppressive strategies. Further,
rejection directly results in approximately 20% of post-transplant
deaths and is believed to play a major role in the development of
late allograft dysfunction and coronary vasculopathy. This book by
international experts in the fields of transplantation medicine,
immunobiology and cardiac imaging provides the reader with an
up-to-date, consise summary of the latest developments in the
diagnosis and treatment of acute cardiac rejection. It is axiomatic
that a more complete understanding of the pathogenic processes
involved in rejection will ultimately lead to its prevention. This
volume will be useful to transplant cardiologists, cardiovascular
surgeons, cardiac pathologists and transplant scientists who seek
to prolong the lifespan and improve the quality of life of their
transplant recipients.
In compiling this textbook on the exciting novel imaging
modality of PET/MRI, the editors have brought together a truly
international group of experts in the field. The book is divided
into two parts. The first part covers methodology and equipment and
includes chapters on basic molecular medicine, contrast agents, MR
attenuation and validation, and quantitative MRI and PET motion
correction. The second part of the book focuses on clinical
applications in oncology, cardiology, and neurology. Imaging of
major neoplasms is covered in a series of individual chapters.
Further chapters address functional and metabolic cardiovascular
examinations and major central nervous system applications such as
brain tumors and dementias. This book will be of interest to all
radiologists and nuclear medicine physicians who wish to learn more
about the latest developments in this important emerging imaging
modality and its applications.
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