Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric disease manifestations, concomitant drug abuse, neuropathies, and an inability to clear viral reservoirs, explain, in large measure, disease progression and immune deterioration. These are associated with a number of psychiatric, muscle, nerve, infectious, as well as cognitive, behavioral, and motor disturbances seen in infected people. Fully updated from the previous two editions and replete with color images, The Neurology of AIDS, Third Edition covers each of these neurological complications and more with a focus on molecular and viral disease processes, cellular factors influencing viral replication therapeutic challenges, and the changing epidemiological patterns of disease. From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field.

This is a major revision of a standard reference work for neuropsychologists, psychiatrists, and neurologists. About one-half of the book contains entirely new work by new contributors. New topics not covered in the previous editions include consideration of common sources of neurocognitive morbidity, such as multiple sclerosis, diabetes, and exposure to heavy metals; psychiatric and behavioral disorders associated wtih traumatic brain injury; neuropsychology in relation to everyday functioning; the effects of cognitive impairment on driving skills, and adherence to medical treatments.
The Third Edition aims to reflect the enormous developments in neuropsychology in terms of research, clinical applications, and growth of the discipline during the past decade. At one time focused on mapping the cognitive and related consequences of brain injuries, research in neuropsychology has now expanded to much broader considerations of the effects of systemic disease, infection, medications, and inflammatory processes on neurocognition and emotion. The Third Edition attemtps to capture these developments while continuing to adhere to the objective of presenting them in a concise manner in a single volume.

The go-to resource for assessing and predicting functional abilities in persons with brain injury or cognitive decline has now been revised and expanded to reflect significant advances in the field. With a focus on key real-world capacities--independent living, vocational functioning, medication management, and driving--leading experts explore how individuals go about their daily lives, where and why disruptions occur, and potential opportunities for improving function. Strategies for direct assessment are reviewed, from standard neuropsychological tests to multimodal approaches and technology-based tools. Chapters also provide functional assessment guidance for specific neurological and psychiatric conditions: dementia, traumatic brain injury, depression, schizophrenia, and others. New to This Edition *Incorporates over a decade of technological and methodological innovations. *Chapter on theories and models of everyday functioning. *Chapters on naturalistic assessment, wearable sensors, ambulatory assessment, and virtual-reality-based tools. *Practical clinical implications are highlighted throughout.