This book constitutes the refereed proceedings of the 13th International Conference on Advances in Optimization and Applications, OPTIMA 2022, held in Petrovac, Montenegro, during September 26-30, 2022. The 13 full papers included in this book were carefully reviewed and selected from 26 submissions. They were organized in topical sections as follows: mathematical programming; global optimization; discrete and combinatorial optimization; optimization and data analysis; game theory and mathematical economics; and applications.

This book constitutes the refereed proceedings of the 13th International Conference on Optimization and Applications, OPTIMA 2022, held in Petrovac, Montenegro, during September 26-30, 2022. The 17 full papers and presented were carefully reviewed and selected from 43 submissions. They were organized into the following as follows: mathematical programming; global optimization; discrete and combinatorial optimization; optimal control; optimization and data analysis; and game theory and mathematical economics.