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Drug-drug interactions are causing morbidity and mortality in
mankind. Severe harmful interactions are recoded when drugs are
prescribed without studying their pharmacokinetic and
pharmacodynamic actions. Knowledge about drug interactions is
necessary for pharmaceutical industries, regulatory agencies,
clinical health care professionals and policy makers. The book
focuses on research findings regarding influence of Fluoroquinolone
(Ciprofloxacin) on the pharmacokinetics of Carbamazepine,
investigated in healthy adult males. Carbamazepine is mostly
prescribed drug for the treatment of epilepsy, neuropathic pain,
schizophrenia, phantom limb syndrome and paroxysmal extreme pain
disorder. Epileptic patients can have various types of infections
like urinary tract, upper respiratory tract, skin and soft tissue,
dental pain, typhoid and other infectious diseases. These patients
often injured during fits and fluoroquinolones are used as first
line of therapy to treat such kind of infectious disease. Since
both drugs are prescribed commonly by the physicians and
interaction may result, so the information about their
pharmacokinetics given here are beneficial for physicians and
researchers.
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