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How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs.
Mulberry, Morus alba L., as a non-toxic natural therapeutic agent, belongs to the family of Moraceae, and has been cultivated in many Asian countries such as China, India, Korea, Japan and Thailand where the leaves were used as food for silkworms. It is a natural food additive having carbohydrates, lipids, proteins, fibres, sugars, vitamins, mineral etc. in appropriate proportion. It is a potent food antioxidant commonly used as a dietary supplement. Researchers suggested that it can be used as a good pharmaceutical food. It has been used since ancient times in folk medicine for its many medicinal properties. The plant has been used in Indian tradition as a nervine tonic. This widely grown plant has been in use by tribals of this country for ailments such as asthma, cough, bronchitis, edema, insomnia, wound healing, diabetes, influenza, eye infections and nose bleeds. The plant extract has been demonstrated to posses free radical scavenging activity. It has been extensively studied for its antidiabetic, antibacterial, antianaphylactic, neuroprotective, hypolipidemic, hypotensive, antiatherosclerotic, anticancer, antidepressant effects.
Lantana camara L. is regarded both as a notorious weed and a popular ornamental garden plant and posseses various uses in folk medicine in many parts of the world. The phytochemical investigation of the methanolic extract of leaves resulted in isolation terpenoidal glycosides namely urosolic acid glycosidic oleiate (NEW), ursolic acid glycosidic stearate (NEW) and oleanolic acid glucoside. Some esters like undecanyl Oleioate, dodecanyl oleioate and carboxylic acids like ursolic acid and oleanolic acid were successfully isolated. HPTLC fingerprint of the methanolic extracts of L. camara leaves were performed. The solvent systems were chloroform: methanol (99:1). Antidiabetic activities of the Lantana camara were performed on streptozotocin induced diabetic rats and the aqueous extracts of both the drugs showed significant reduction in blood glucose level.
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