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Molecular docking plays an important role in the process of drug discovery; specifically in virtual screening of combinatorial libraries and optimization of the lead compounds. The ability to model and predict the binding sites of proteins on one hand and in silico screening of large number of compounds on the other hand has encouraged the development of new algorithms and streatgies for docking programs. While docking does not completely eliminate the need for experiments, lab-on-chip type of approaches coupled with computational high throughput screening have been a boon to the drug discovery activity. It will help in reducing the cost of novel drug development. In the current book on computational drug discovery, we described small information about the case study of drug development against Tuberculosis and Herpes diseases. In later case study, we provided detail description about protein modeling to natural drug finding against Cholera disease.
The medicinal plants and herbs are used for many years. Medicinal plants have several secondary metabolites which are helpful for curing of diseases. Some of the herbs are used as growth production, higher FCR, intake, immuno-stimulant, liver tonic, anti-oxidants and for reducing cholesterol. Now-a-days, utilization of these medicinal plants is increasing in another field such as feed additives. If we talk about humans there are several herbal additives for improvement of human digestive system. Herbal additives are also beneficial for animal production example Leaves of Azadirachta indica are used for feeding and reducing the parasitic load of animals. Small amount of Herbs can improve growth, intake, meat, milk etc. So in this book, we are going to focus about goat digestive system and how can goat production improve by herbal additives?
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