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This book is intended both to be an introduction to techniques and
applications of liquid chromatography/mass spectrometry and to
serve as a reference for future workers. When we undertook its
writing, we chose not to cover the field, particularly
applications, exhaustively. Rather we wished to produce a book that
would be of use to people just beginning to use the technique as
well as to more advanced practitioners. In this regard, we have
sought to highlight techniques and applications that are of current
importance, while not neglecting descriptions of approaches that
may be of significance in the future. We hope that we have
succeeded in this. At the same time we hope that the bibliography,
with indexes classified by author and title, will make this book of
value to those who may disagree with our emphasis. ACKNOWLEDGMENTS.
One of us (C. G. E. ) wishes to acknowledge the en couragment of
Professor J. A. McCloskey in undertaking this project. All four of
us are grateful for the continuous and expert assistance of V. A.
Edmonds in the preparation of the Bibliography. Alfred L. Y ergey
Bethesda, Maryland Charles G. Edmonds Richland, Washington lvor A.
S. Lewis London, England Marvin L. Vestal Houston, Texas v Contents
1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . 1
. . . . . . . . . . . 2. Direct Liquid Introduction Interfaces . .
. . . . . . . . 5 . . . 2. 1. Introduction . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
5 2. 2. Operating Principles . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . 7 2. 3. Specific DLI
Interfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . 10 2. 3. 1. Capillary Inlets . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2. 3. 2.
Diaphragm Interfaces . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . 12 2. 3. 3. Nebulizing Interfaces . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . ."
This book is intended both to be an introduction to techniques and
applications of liquid chromatography/mass spectrometry and to
serve as a reference for future workers. When we undertook its
writing, we chose not to cover the field, particularly
applications, exhaustively. Rather we wished to produce a book that
would be of use to people just beginning to use the technique as
well as to more advanced practitioners. In this regard, we have
sought to highlight techniques and applications that are of current
importance, while not neglecting descriptions of approaches that
may be of significance in the future. We hope that we have
succeeded in this. At the same time we hope that the bibliography,
with indexes classified by author and title, will make this book of
value to those who may disagree with our emphasis. ACKNOWLEDGMENTS.
One of us (C. G. E. ) wishes to acknowledge the en couragment of
Professor J. A. McCloskey in undertaking this project. All four of
us are grateful for the continuous and expert assistance of V. A.
Edmonds in the preparation of the Bibliography. Alfred L. Y ergey
Bethesda, Maryland Charles G. Edmonds Richland, Washington lvor A.
S. Lewis London, England Marvin L. Vestal Houston, Texas v Contents
1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . 1
. . . . . . . . . . . 2. Direct Liquid Introduction Interfaces . .
. . . . . . . . 5 . . . 2. 1. Introduction . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
5 2. 2. Operating Principles . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . 7 2. 3. Specific DLI
Interfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . 10 2. 3. 1. Capillary Inlets . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2. 3. 2.
Diaphragm Interfaces . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . 12 2. 3. 3. Nebulizing Interfaces . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . ."
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