The purpose of this study was to investigate the interoperability among different health care organizations. The knowledge of this study would be supportive to health care organizations to understand the interoperability problems in health care organizations. In the first phase of literature review interoperability challenges in Sweden and other EU countries were identified. On the basis of findings interviews were conducted to know the strategies and planning about interoperability in health care organizations. After analysis of interviews, questionnaires were conducted to know the opinions of different medical IT administrator and health professionals.