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It is in the receptors of the vertebrate retina that the
characteristic visual process - the transduction of radiational
energy into physiological activtty of a different kind - takes
place. The way these receptors modify or redistribute the incident
radiation and thereby control the light ab sorption by the visual
pigments they contain, is the central theme of this book. As far
back as 1843 Brucke put forward a well-reasoned model for the
optics of a receptor, assuming simple ray optics, and it is already
some forty-seven years since the dependence of receptor sensitivity
on retinal angle of incidence was established experimentally as an
important factor in human vision and as one by which the direction
of alignment of receptors in the living eye might be determined.
But it is to Professor J. M. Enoch, editor and author of several
major contributions to this volume, that we owe the first
experimental demonstration (in 1961) of the wave-mode propa gation
of light in vertebrate visual receptors, as well as the results of
some thirty years devoted research concerned with all questions of
receptor optics, particularly directional sensitivity and receptor
alignment, both for normal vertebrate eyes and for pathologically
modified eyes. His work on the latter has opened up a whole range
of clinical possibilities."
When seen from an outsider's vantage point, the development of
knowledge in the sensory sciences must appear massive and the
result of some carefully followed master plan. In reality, it is
the result of numerous relatively independent human endeavors
shaped by application of the scientific method. The comprehensive
construction of quantitative theories of sense organ function has
occurred only recently -but at an explosive rate prefaced by
centuries of expansion in the physical sciences. Predicated on this
growth, the twentieth century may become known as the age of the
biological sciences. With the exception of a modest number of
intellectual giants, there were few contributors to the foundations
of the sensory sciences before the dawn of this century. At least
90% of existing knowledge has been produced by scientists working
in laboratories founded since 1920. If any single scientist and his
laboratory may be identified with the growth in the sensory
sciences, it is EDGAR DOUGLAS ADRIAN, First Baron of Cambridge and
leader of the Physiological Laboratory at Cambridge University,
England. Lord ADRIAN'S influence upon the sensory sciences was
great, not only in terms of his contribution to knowledge itself
but also through the influence which he exerted upon numerous young
scientists who spent weeks or years at the Cambridge laboratory and
who later returned to their homelands and colleagues with the seeds
of vigorous research and quantitative inquiry firmly implanted.
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