Withtherecentlyperceivedincreaseinincidenceofautismandtherealizationthat "autism"mayactuallybe"autisms"withsubsetsofaffectedindividuals,researchers have been pursuing the possibility that there may be multiple etiologies for the disorder.Althoughmostautismstudieshavefocusedongeneticsandadvancedn- roimaging,thereisapaucityofresearchaimedatdeterminingtheneurochemical basisofautism.Identifyingcoreneuralsubstratesorkeybiomarkersisessentialto understandingthemechanisticbasisthatmayinpartunderlie"autisms."Alterations inmolecules,proteins,receptors,andsynapticelementsaresomeofthecontrib- ingsubstratesthatcouldresultinaltereddevelopmentalprocesses,changedsynaptic function,andaberrationsinconnectivity.Itisnowapparentthatmultiplebrainareas are affected in autism, and neuropathological defects have been described within corticalandsubcorticalnetworks.Althoughrecentprogresshasbeenmadeinid- tifyingsomeofthegenesthatmayunderliethedisorder,muchattentionhasalso beengiventoepigeneticand/orenvironmentalfactorsthatmaycontributetosubsets ofautisticindividuals. The contributors to this book were hand selected because of their expertise in their respective ?elds. Individually each chapter presents a unique perspective into the clinical, developmental, neurochemical, and/or physical chemical basis of autism. The contributing authors summarize current research ?ndings in their respective areas and also present novel ideas and propose hypotheses and p- sible mechanisms that may be operative during development and the potential consequencesofhavingdefectsinspeci?cmolecules,receptors,orgenes. Thesubtitle"FromMoleculestoMinicolumns"wasinsertedbecauseofmuch recent attention given to alterations in the basic organization of mini- or mic- columns of neurons in cerebral cortical areas in autism. These especially include prefrontalcorticalareasthatundergoanovergrowthduringearlypostnataldevel- mentinmanyindividualswithautism.Tothisend,theworldrenownedDr.Alan Peters,theneuroanatomistthatoriginallydescribedmini-ormicro-columnaror- nizationinthecerebralcortex,wasrecruitedtowriteachapterinthisbookgiving hisexpertperspectiveontheissueinautism. The book begins with highly respected clinician, Dr. Margaret L. Bauman, DirectoroftheLADDERSclinicintheBostonarea,withaclinicalandmedicalp- spectiveofautismdiscussingetiologies,clinicalpresentation,earlyidenti?cation, vii viii Preface advancementsinmedicalcare,andassociateddisorders. Inthechapter"TheMale Prevalence in Autism Spectrum Disorders: Hypotheses on its Neurobiological Basis",ItalianresearchersDrs.FlavioKellerandLilianaRutapresentneuroch- ical hypotheses as the basis for the predominance of male prevalence in autism discussing the possible roles of estrogen, testosterone, oxytocin, and vasopressin in the organization of brain circuits and hemispheric specialization. Psychiatrist Dr. Ricardo Vella relates neuropathologies in autism, in the limbic and cereb- lar regions, to speci?c behaviors and presents a developmental perspective and hypotheses regarding emotional and attachment behaviors in autistic individuals.

Analytics - Business Intelligence, Algorithms and Statistical Analysis In today's world, analysis has become an extremely important aspect to consider when you are thinking of starting any new line of business or even when it comes to purchasing a new house. The unfortunate fact is that not many people know what analysis is all about. They tend to assume that each of the elements - analysis, business intelligence, algorithms and statistical analysis - are different entities when in reality they are all interlinked. This book will help you gather a greater insight on all the elements. And you will gain an in-depth knowledge on each of these elements in different parts of the book; helping you to increase your knowledge and widen your horizons!

The main focus of this monograph is synthesizing the importance of geographic approaches to public health and patient care. The chapters are organized into four themed sections: the role of geography in health care reform; the geographies of human health; geospatial data and technologies; and geography in medicine. It is a highly informative book, providing scientific insight for geographers with an interest in advanced geospatial applications and health research. The author is an international expert in geography, GIS, and public health, who co-edited a special issue on "Geospatial Applications in Disease Surveillance," published in the International Journal of Applied Geospatial Research. "Health, Science, and Place is a well-intentioned overview of medical geography in the context of the ACA. Blatt does an excellent job synthesizing ecologic and geographic literatures with what we know about individual health, health care systems, and public health. ... this book fills a need in the field by offering a timely discussion of the ACA and medical geography." - Jennifer L. Moss, The AAG Review of Books, Vol. 4 (2), 2016 "Amy Blatt's pioneering new book on geomedicine and its exciting capacity to promote health and minimize risk is a robust call for understanding the role of geography for everyone's quality of life. In Health, Science, and Place: A New Mode, Dr. Blatt's contributions can be summarized in three categories: comprehensive analysis, creative curating, and targeted innovations... Overall, Dr. Blatt's Health, Science, and Place: A New Model is a pathbreaking book challenging all public health and health communication scholars and practitioners to explore vigorously the role of medical geography as a shining new bridge between geography and patient care." - John C. Pollock, PhD, MPA, Professor of Health Communication and Human Rights, and Faculty Affiliate in Public Health, The College of New Jersey, Ewing, NJ

The papers featured in "Attachment and Sexuality "create a dense tapestry, each forming a separate narrative strand that elucidates different configurations of the relationship between attachment and sexuality. As a whole, the volume explores the areas of convergence and divergence, opposition, and integration between these two systems. It suggests that there is a bi-directional web of influences that weaves the attachment and sexual systems together in increasingly complex ways from infancy to adulthood.
The volume's unifying thread is the idea that the attachment system, and particularly the degree of felt security, or lack thereof in relation to early attachment figures, provides a paradigm of relatedness that forms a scaffold for the developmental unfolding of sexuality in all its manifestations. Such manifestations include infantile and adult, masturbatory and mutual, and normative and perverse. Also central to the papers is the idea that the development of secure attachment is predicated, in part, on the development of the capacity for mentalization, or the ability to envision and interpret the behavior of oneself and others in terms of intentional mental states, including desires, feelings, beliefs, and motivations. Topics discussed in the book will help to shape the direction and tenor of further dialogues in the arena of attachment and sexuality.

Dynamic psychotherapy research has become revitalized, especially in the last three decades. This major study by Sidney Blatt, Richard Ford, and their associates evaluates long-term intensive treatment (hospital ization and 4-times-a-week psychotherapy) of very disturbed patients at the Austen Riggs Center. The center provides a felicitous setting for recovery-beautiful buildings on lovely wooded grounds just off the quiet main street of the New England town of Stockbridge, Massa chusetts. The center, which has been headed in succession by such capable leaders as Robert Knight, Otto Will, Daniel Schwartz, and now Edward Shapiro, has been well known for decades for its type of inten sive hospitalization and psychotherapy. Included in its staff have been such illustrious contributors as Erik Erikson, David Rapaport, George Klein, and Margaret Brenman. The Rapaport-Klein study group has been meeting there yearly since Rapaport's death in 1960. Although the center is a long-term care treatment facility, it remains successful and solvent even in these days of increasingly short-term treatment. Sidney Blatt, Professor of Psychology and Psychiatry at Yale Univer sity, and Richard Ford of the Austen Riggs Center, and their associates assembled a sample of 90 patients who had been in long-term treatment and who had been given (initially and at 15 months) a set of psychologi cal tests, including the Rorschach, the Thematic Apperception Test, a form of the Wechsler Intelligence Test, and the Human Figure Drawings."

The papers featured in Attachment and Sexuality create a dense tapestry, each forming a separate narrative strand that elucidates different configurations of the relationship between attachment and sexuality. As a whole, the volume explores the areas of convergence and divergence, opposition, and integration between these two systems. It suggests that there is a bi-directional web of influences that weaves the attachment and sexual systems together in increasingly complex ways from infancy to adulthood. The volume's unifying thread is the idea that the attachment system, and particularly the degree of felt security, or lack thereof in relation to early attachment figures, provides a paradigm of relatedness that forms a scaffold for the developmental unfolding of sexuality in all its manifestations. Such manifestations include infantile and adult, masturbatory and mutual, and normative and perverse. Also central to the papers is the idea that the development of secure attachment is predicated, in part, on the development of the capacity for mentalization, or the ability to envision and interpret the behavior of oneself and others in terms of intentional mental states, including desires, feelings, beliefs, and motivations. Topics discussed in the book will help to shape the direction and tenor of further dialogues in the arena of attachment and sexuality.

Examines theoretical aspects of attachment research and psychoanalysis. Topics covered include similarities and differences between psychoanalytic and attachment theories, the development of caregiving, and the two-person unconscious.

First published in 1999. Routledge is an imprint of Taylor and Francis, an informa company.

Recent research indicates that depression, once believed to be relatively benign, is highly recurrent and does not respond well to treatment. The goal of this book is to facilitate the development of more encompassing theories and more effective treatments for this disabling disorder by fostering dialogue and enhancing the integration of work across the boundaries of separate fields.

The main focus of this monograph is synthesizing the importance of geographic approaches to public health and patient care. The chapters are organized into four themed sections: the role of geography in health care reform; the geographies of human health; geospatial data and technologies; and geography in medicine. It is a highly informative book, providing scientific insight for geographers with an interest in advanced geospatial applications and health research. The author is an international expert in geography, GIS, and public health, who co-edited a special issue on "Geospatial Applications in Disease Surveillance," published in the International Journal of Applied Geospatial Research. "Health, Science, and Place is a well-intentioned overview of medical geography in the context of the ACA. Blatt does an excellent job synthesizing ecologic and geographic literatures with what we know about individual health, health care systems, and public health. ... this book fills a need in the field by offering a timely discussion of the ACA and medical geography." - Jennifer L. Moss, The AAG Review of Books, Vol. 4 (2), 2016 "Amy Blatt's pioneering new book on geomedicine and its exciting capacity to promote health and minimize risk is a robust call for understanding the role of geography for everyone's quality of life. In Health, Science, and Place: A New Mode, Dr. Blatt's contributions can be summarized in three categories: comprehensive analysis, creative curating, and targeted innovations... Overall, Dr. Blatt's Health, Science, and Place: A New Model is a pathbreaking book challenging all public health and health communication scholars and practitioners to explore vigorously the role of medical geography as a shining new bridge between geography and patient care." - John C. Pollock, PhD, MPA, Professor of Health Communication and Human Rights, and Faculty Affiliate in Public Health, The College of New Jersey, Ewing, NJ

Withtherecentlyperceivedincreaseinincidenceofautismandtherealizationthat "autism"mayactuallybe"autisms"withsubsetsofaffectedindividuals,researchers have been pursuing the possibility that there may be multiple etiologies for the disorder.Althoughmostautismstudieshavefocusedongeneticsandadvancedn- roimaging,thereisapaucityofresearchaimedatdeterminingtheneurochemical basisofautism.Identifyingcoreneuralsubstratesorkeybiomarkersisessentialto understandingthemechanisticbasisthatmayinpartunderlie"autisms."Alterations inmolecules,proteins,receptors,andsynapticelementsaresomeofthecontrib- ingsubstratesthatcouldresultinaltereddevelopmentalprocesses,changedsynaptic function,andaberrationsinconnectivity.Itisnowapparentthatmultiplebrainareas are affected in autism, and neuropathological defects have been described within corticalandsubcorticalnetworks.Althoughrecentprogresshasbeenmadeinid- tifyingsomeofthegenesthatmayunderliethedisorder,muchattentionhasalso beengiventoepigeneticand/orenvironmentalfactorsthatmaycontributetosubsets ofautisticindividuals. The contributors to this book were hand selected because of their expertise in their respective ?elds. Individually each chapter presents a unique perspective into the clinical, developmental, neurochemical, and/or physical chemical basis of autism. The contributing authors summarize current research ?ndings in their respective areas and also present novel ideas and propose hypotheses and p- sible mechanisms that may be operative during development and the potential consequencesofhavingdefectsinspeci?cmolecules,receptors,orgenes. Thesubtitle"FromMoleculestoMinicolumns"wasinsertedbecauseofmuch recent attention given to alterations in the basic organization of mini- or mic- columns of neurons in cerebral cortical areas in autism. These especially include prefrontalcorticalareasthatundergoanovergrowthduringearlypostnataldevel- mentinmanyindividualswithautism.Tothisend,theworldrenownedDr.Alan Peters,theneuroanatomistthatoriginallydescribedmini-ormicro-columnaror- nizationinthecerebralcortex,wasrecruitedtowriteachapterinthisbookgiving hisexpertperspectiveontheissueinautism. The book begins with highly respected clinician, Dr. Margaret L. Bauman, DirectoroftheLADDERSclinicintheBostonarea,withaclinicalandmedicalp- spectiveofautismdiscussingetiologies,clinicalpresentation,earlyidenti?cation, vii viii Preface advancementsinmedicalcare,andassociateddisorders. Inthechapter"TheMale Prevalence in Autism Spectrum Disorders: Hypotheses on its Neurobiological Basis",ItalianresearchersDrs.FlavioKellerandLilianaRutapresentneuroch- ical hypotheses as the basis for the predominance of male prevalence in autism discussing the possible roles of estrogen, testosterone, oxytocin, and vasopressin in the organization of brain circuits and hemispheric specialization. Psychiatrist Dr. Ricardo Vella relates neuropathologies in autism, in the limbic and cereb- lar regions, to speci?c behaviors and presents a developmental perspective and hypotheses regarding emotional and attachment behaviors in autistic individuals.

The first International Conference on Thermoelectric Properties of Metallic Conductors was held at Michigan State University on August 10-12, 1977. The conference was sponsored and supported by the National Science Foundation, the Office of Naval Research and the Ford Motor Company. Although the topic may appear, at first glance, rather narrow and of limited interest, it impacts significantly on numerous fields of research, in each instance providing a unique and fru- ful technique for securing important data that is frequently difficult to obtain by other means. Thus, though thermoelectricity is the thread that binds these pages together, the papers constitute a patchwork quilt that includes critical phenomena, superconductivity, many-body theory, quasi one-dimensional systems, liquid metals, to mention only a few. This volume contains the 12 invited and 31 contributed papers, arranged in the order in which they were presented, as well as much of the frequently spirited and always illuminating discussion that followed these papers. Regrettably, not all of the discussion is included. Difficulties with the recording system during the first session (Wednesday morning) did not become apparent before the end of that session, and, consequently, none of the discussion--some of it fairly heated--appears in the proceedings; other remarks were lost to posterity through occasional malfunctioning of the record ing facilities and/or failure of speakers to come near a microphone."

Dynamic psychotherapy research has become revitalized, especially in the last three decades. This major study by Sidney Blatt, Richard Ford, and their associates evaluates long-term intensive treatment (hospital ization and 4-times-a-week psychotherapy) of very disturbed patients at the Austen Riggs Center. The center provides a felicitous setting for recovery-beautiful buildings on lovely wooded grounds just off the quiet main street of the New England town of Stockbridge, Massa chusetts. The center, which has been headed in succession by such capable leaders as Robert Knight, Otto Will, Daniel Schwartz, and now Edward Shapiro, has been well known for decades for its type of inten sive hospitalization and psychotherapy. Included in its staff have been such illustrious contributors as Erik Erikson, David Rapaport, George Klein, and Margaret Brenman. The Rapaport-Klein study group has been meeting there yearly since Rapaport's death in 1960. Although the center is a long-term care treatment facility, it remains successful and solvent even in these days of increasingly short-term treatment. Sidney Blatt, Professor of Psychology and Psychiatry at Yale Univer sity, and Richard Ford of the Austen Riggs Center, and their associates assembled a sample of 90 patients who had been in long-term treatment and who had been given (initially and at 15 months) a set of psychologi cal tests, including the Rorschach, the Thematic Apperception Test, a form of the Wechsler Intelligence Test, and the Human Figure Drawings.

Thermoelectric and related transport properties of metals have been a source of information and, also, exasperation to physicists for over a century. Perhaps the principal reasons for interest in these phenomena are their sensitivity to composition, structure and external fields and, until fairly recently, the distressing fact that often even gross experimental features such as the sign of the thermopower eluded theoretical understanding. During the past two decades many of the previously perplexing aspects of thermoelectricity have yielded to more sophisticated theoretical treat ment. As a result of this effort and concomitant experimental work using advanced measurement techniques, there is now good reason to believe that thermoelectric phenomena can shed much light on the interactions between electrons and phonons, impurities, and other defects. The last few years have witnessed new and fascinating developments that promise to stimulate new activity in this field. In contrast to the more conventional transport properties, second-and high-order contributions in electron scattering theory appear to play a profound role in thermoelectricity-the controversy surrounding ordinary and "phony" phonon drag is far from resolved; the startlingly large effect of magnetic fields on the thermopower of metals appears to be linked intimately to scattering anisotropy; quantum oscillations of thermopower are orders of magnitude larger than corresponding oscillations of the magnetoresistance; a new approach to thermoelectric studies allows extension of thermopower measurements into the millikelvin region of temperature; finally, the advent of superconducting detection devices permits the precise measurement of extremely small voltages, an essential requirement in this field."

Medical geography is a fascinating area of rapidly evolving study that aims to analyse and improve worldwide health issues based on the geographical factors which have an impact on them. Perspectives in Medical Geography will appeal to both novice and seasoned researchers looking to be informed on the latest theories and applications in the field. Chapters represent a wide range of industries, ranging from private/public universities to private companies to non-profit foundations. Contributors describe ways in which map and geography librarians can engage in public health research - creating data standards, archiving map collections and providing mapping/GIS services. In addition to compiling current theories and practices related to medical geography, this volume also features commentaries from two pre-eminent geography librarians, sharing their perspectives on this emerging field and how map and geographic information librarians can engage in health-related research through their profession. This book was originally published as two special issues of the Journal of Map & Geography Libraries.

The look and feel of metropolitan France has been a notable preoccupation of French literary and visual culture since the 1980s. Numerous writers, filmmakers and photographers have been drawn to articulate France's contrasting spatial qualities, from infrastructural installations such as roads, rail lines and ports, to peri-urban residential developments and isolated rural enclaves. In doing so, they explore how the country's acute sense of national identity has been both asserted and challenged in topographic terms. This wide-ranging collection of essays explores how the contemporary concern with space in France has taken shape across a range of media, from recent cinema, documentary filmmaking and photographic projects through to television drama and contemporary fiction, and examines what it reveals about the state of the nation in a post-colonial and post-industrial age. The impact of global flows of capital, trade and migration can be mapped through attention to the specificities of place and topography. Investigation of liminal locations, from seaboard cities and abandoned industrial sites to refugee camps and peasant smallholdings, interrogates the assertion of a national territory (and, by extension, a national identity) through the figure of the hexagon, and highlights the fluidities, instabilities and lines of flight which render it increasingly unsettled.

The look and feel of metropolitan France has been a notable preoccupation of French literary and visual culture since the 1980s. Numerous writers, filmmakers and photographers have been drawn to articulate France's contrasting spatial qualities, from infrastructural installations such as roads, rail lines and ports, to peri-urban residential developments and isolated rural enclaves. In doing so, they explore how the country's acute sense of national identity has been both asserted and challenged in topographic terms. This wide-ranging collection of essays explores how the contemporary concern with space in France has taken shape across a range of media, from recent cinema, documentary filmmaking and photographic projects through to television drama and contemporary fiction, and examines what it reveals about the state of the nation in a post-colonial and post-industrial age. The impact of global flows of capital, trade and migration can be mapped through attention to the specificities of place and topography. Investigation of liminal locations, from seaboard cities and abandoned industrial sites to refugee camps and peasant smallholdings, interrogates the assertion of a national territory (and, by extension, a national identity) through the figure of the hexagon, and highlights the fluidities, instabilities and lines of flight which render it increasingly unsettled.

Authoritative and comprehensive, this volume provides a contemporary psychodynamic perspective on frequently encountered psychological disorders in adults, children, and adolescents. Leading international authorities review the growing evidence base for psychoanalytic theories and therapeutic models. Chapters examine the etiology and psychological mechanisms of each disorder and thoroughly describe effective treatment strategies. Highly accessible, the book is richly illustrated with clinical case material. It demonstrates ways in which psychodynamic theory and therapy are enhanced by integrating ideas and findings from neuroscience, social and personality psychology, cognitive-behavioral therapy, and other fields. Winner-Goethe Award for Psychoanalytic and Psychodynamic Scholarship

The explosive proliferation of pictures in advertising and pop culture, mass media, and cyberspace following World War II, along with the profusion of critical thinking that tries to make sense of it, has had wide-ranging implications for cultural production as such. "Pictures into Words" explores how this proliferation of graphic images has profoundly affected narrative writing in France, especially, as Ari J. Blatt argues, the structure, content, and symbolic logic of contemporary French fiction. By examining a specific corpus of narratives by authors Claude Simon, Georges Perec, Pierre Michon, and Tanguy Viel--books that originate amid, conjure up, and indeed are essentially about pictures--Blatt addresses the most salient questions pertaining to the relationship between literature and visual culture today.
Each of the novels considered here engages the work of several postwar artists, from Robert Rauschenberg, Andy Warhol, Vincent van Gogh, and Orson Welles to Jeff Koons, Joseph L. Mankiewicz, Pierre Huyghe, and Marcel Duchamp. As Blatt's cross-disciplinary readings show, despite their gleeful raiding of the visual archive to generate and enrich their stories, many contemporary narratives that tell tales about pictures simultaneously express a cautious skepticism toward vision and visual representation. "Pictures into Words" examines how such novels, while seemingly complicit with the visual, simultaneously "write back" against the images they exploit, reclaiming some of literature's lost ground in our visually inundated world.

Recent research indicates that depression, once believed to be relatively benign, is highly recurrent and does not respond well to treatment. The goal of this book is to facilitate the development of more encompassing theories and more effective treatments for this disabling disorder by fostering dialogue and enhancing the integration of work across the boundaries of separate fields. Each chapter offers an overview of the state of the art of research in a particular area - cognitive-behavioral therapy, psychodynamic therapy, epidemiology, developmental psychopathology, neurobiology - and explores both the implications of the latest hypotheses and findings for work in other areas and the barriers to constructive collaboration. In an integrative Epilogue, the editors identify and discuss the points of primary convergence. They note dissatisfaction with the DSM approach to depression because it is insufficiently informed by basic research, and with existing guidelines for intervention because they underestimate the need for more extended treatments for many patients, the importance of patient and therapist factors, and the central role of the therapeutic alliance. etiologically-based, dynamic interactionism model of depression that emphasizes recursive interactions among genetic and neurobiological factors, personality, and life stress in etiology. Finally, they reflect on the potential of this dynamic interactionism model to guide future research on mood disorders and the formulation of treatment guidelines that are better informed by science and more congruent with complex clinical reality.

Authoritative and comprehensive, this volume provides a contemporary psychodynamic perspective on frequently encountered psychological disorders in adults, children, and adolescents. Leading international authorities review the growing evidence base for psychoanalytic theories and therapeutic models. Chapters examine the etiology and psychological mechanisms of each disorder and thoroughly describe effective treatment strategies. Highly accessible, the book is richly illustrated with clinical case material. It demonstrates ways in which psychodynamic theory and therapy are enhanced by integrating ideas and findings from neuroscience, social and personality psychology, cognitive-behavioral therapy, and other fields. Winner--Goethe Award for Psychoanalytic and Psychodynamic Scholarship