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A timely book for DNA researchers, Automated DNA Sequencing and
Analysis reviews and assesses the state of the art of automated DNA
sequence analysis-from the construction of clone libraries to the
developmentof laboratory and community databases. It presents the
methodologies and strategies of automated DNA sequence analysis in
a way that allows them to be compared and contrasted. By taking a
broad view of the process of automated sequence analysis, the
present volume bridges the gap between the protocols supplied with
instrument and reaction kits and the finalized data presented in
the research literature. It will be an invaluable aid to both small
laboratories that are interested in taking maximum advantageof
automated sequence resources and to groups pursuing large-scale
cDNA and genomic sequencing projects.
* The field of automation in DAN sequencing and analysis is rapidly
moving. Hovever, as the technology becomes commonplace, those
applying the techniques involved to their research fields need a
text which both expands on the protocols supplied by manufacturers
with their instruments and explains how to utilise the data
produced. This book fulfils those needs, reviews the history of the
art and provides pointers to future development.
Race, while drawn from the visual cues of human diversity, is an
idea with a measurable past, an identifiable present, and an
uncertain future. The concept of race has been at the center of
both triumphs and tragedies in American history and has had a
profound effect on the human experience. "Race Unmasked" revisits
the origins of commonly held beliefs about the scientific nature of
racial differences, examines the roots of the modern idea of race,
and explains why race continues to generate controversy as a tool
of classification even in our genomic age.
Through rigorous historical research, "Race Unmasked" reveals
how genetics and related biological disciplines formed and
preserved ideas of race and, at times, racism throughout the
twentieth century. Surveying the work of some of the twentieth
century's most notable scientists, the book tests and then proves
the limitations of a racial worldview. This new work is a gripping
history of science and scientists that throws the contours of our
current and evolving understanding of human diversity into sharp
relief.
Race, while drawn from the visual cues of human diversity, is an
idea with a measurable past, an identifiable present, and an
uncertain future. The concept of race has been at the center of
both triumphs and tragedies in American history and has had a
profound effect on the human experience. Race Unmasked revisits the
origins of commonly held beliefs about the scientific nature of
racial differences, examines the roots of the modern idea of race,
and explains why race continues to generate controversy as a tool
of classification even in our genomic age. Surveying the work of
some of the twentieth century's most notable scientists, Race
Unmasked reveals how genetics and related biological disciplines
formed and preserved ideas of race and, at times, racism. A
gripping history of science and scientists, Race Unmasked
elucidates the limitations of a racial worldview and throws the
contours of our current and evolving understanding of human
diversity into sharp relief.
Upon completing his historic work on the Human Genome Project in
2002, J. Craig Venter declared that he would sequence the genetic
code of all life on earth. Thus began a fifteen-year quest to
collect DNA from the world's oldest and most abundant form of life:
microbes. Boarding the Sorcerer II, a 100-foot sailboat turned
research vessel, Venter travelled over 65,000 miles around the
globe to sample ocean water and the microscopic life within. In
this book, Venter and science writer David Ewing Duncan tell the
remarkable story of these expeditions and of the momentous
discoveries that ensued-of plant-like bacteria that get their
energy from the sun, proteins that metabolize vast amounts of
hydrogen, and microbes whose genes shield them from ultraviolet
light. The result was a massive library of millions of unknown
genes, thousands of unseen protein families, and new lineages of
bacteria that revealed the unimaginable complexity of life on
earth. Yet despite this exquisite diversity, Venter encountered
sobering reminders of how human activity is disturbing the delicate
microbial ecosystem that nurtures life on earth. In the face of
unprecedented climate change, Venter and Duncan show how we can
harness the microbial genome to develop alternative sources of
energy, food, and medicine that might ultimately avert our
destruction. A captivating story of exploration and discovery, this
book restores microbes to their rightful place as crucial partners
in our evolutionary past and guides to our future.
In 2010, scientists led by J. Craig Venter became the first to
successfully create 'synthetic life' -- putting humankind at the
threshold of the most important and exciting phase of biological
research, one that will enable us to actually write the genetic
code for designing new species to help us adapt and evolve for
long-term survival. The science of synthetic genomics will have a
profound impact on human existence, including chemical and energy
generation, health, clean water and food production, environmental
control, and possibly even our evolution. In Life at the Speed of
Light, Venter presents a fascinating and authoritative study of
this emerging field from the inside -- detailing its origins,
current challenges and controversies, and projected effects on our
lives. This scientific frontier provides an opportunity to ponder
anew the age-old question 'What is life?' and examine what we
really mean by 'playing God'. Life at the Speed of Light is a
landmark work, written by a visionary at the dawn of a new era of
biological engineering.
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