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"Epigenetic Regulation in the Nervous System" addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winningvolume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this
book offers a comprehensive review of behavioral epigenetics and a
balanced treatment of the strengths and weaknesses in
experimentation in this area. Covering background material as well
as topics of current interest, it serves both as a cutting-edge
resource and a foundational reference. The book will benefit
neuroscience researchers and graduate students with an interest in
the links between gene regulation and behavior, as will clinicians
dealing with disorders such as addiction, depression, and
schizophrenia.
This fully revised 2e provides the only unified synthesis of
available information concerning the mechanisms of higher-order
memory formation. It spans the range from learning theory, to human
and animal behavioral learning models, to cellular physiology and
biochemistry. It is unique in its incorporation of chapters on
memory disorders, tying in these clinically important syndromes
with the basic science of synaptic plasticity and memory
mechanisms. It also covers cutting-edge approaches such as the use
of genetically engineered animals in studies of memory and memory
diseases. Written in an engaging and easily readable style and
extensively illustrated with many new, full-color figures to help
explain key concepts, this book demystifies the complexities of
memory and deepens the reader s understanding.
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