This book is a practical, step-by-step guide to the management of orthopaedic fractures. In an aging population and with greater participation in contact sports, the incidence of fractures is on the increase, and conversely the amount of hands-on experience that orthopaedic trainees receive is declining. The book provides a detailed manual of the management of orthopaedic trauma. It includes indications for surgery, initial management and theatre set-up and equipment, step-by-step technique with cadaveric photographs showing the surgical approaches, and complications and their avoidance. Pre- and post-operative radiological images are also included as well as ‘tips and tricks of the trade’ to ensure a successful outcome.

Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies. This title is a perfect reference for clinical pathologists, laboratory scientists, medical technologists, physicians specializing in oncology, internal medicine, family practice and transplant medicine, resident physicians, medical students, nurse practitioners and clinical chemists.

This book is the follow-up of the Boost Volume I book and it has been written for software developers who use Boost C++ libraries to create flexible applications. We discuss approximately 20 advanced libraries that can be classified into the following major categories: Mathematics: special functions, statistical distributions, interval arithmetic and matrix algebra. Special data structures: date and time, circular buffer, UUID, dynamic bitsets, pool memory. TCP and UDP portable network programming using the software interface. Interprocess communication and shared memory programming models. Three chapters on graphs, graph algorithms and their implementation in Boost. The focus is hands-on and each library is discussed in detail and numerous working examples are given to get the reader up to speed as soon as possible. Each library is described in a step-by-step fashion and you can use the corresponding code as a basis for more advanced applications. These libraries are the ideal basis for new applications. We shall use them in Volume III of the current series when we discuss applications to engineering, science and computational finance. About the Authors Robert Demming is software designer, developer and trainer and he has been involved with software projects in the areas of optical technology, process control, CAD and order processing systems since 1993. He has a BSc degree in technical computerscience from Amsterdam Hogeschool. Daniel J. Duffy is founder of Datasim Education BV and has been working with C++ and its applications since 1989 and with software development since 1979. He is designer, algorithm builder and trainer. He has a PhD in numerical analysis from Trinity College, Dublin. One of the projects that he is involved in is applying the Boost libraries to computational finance."

C++ is one of the most important and influential programming languages for application development. It supports the modular, object- oriented and generic programming models and its flexibility has been one of the main reasons why it has been so successful. With the emergence of the Boost Libraries (www.boost.org) we see that C++ is brought to a new level, namely a set of reusable and modular template libraries that C++ developers can use in their applications. This book is dedicated to a number of Boost libraries for higher-order functions, data types and data structures, libraries for text and string processing, multi-threading, random number generation and more. We also discuss how Boost and design patterns are used to promote the flexibility of code. Each library is described in a step-by-step manner. Numerous examples are given to show the functionality of each library. The full source code is freely available to purchasers of the book. Coverage Includes Understanding and using 30 major Boost libraries. Learn about higher-order functions, data structures, memory management, multi-threading and more. Using Boost in new and existing applications. Integrating Boost and the Gang-Of-Four design patterns. Ready-to-run projects for Visual Studio. Appendices and exercises."

The world of quantitative finance (QF) is one of the fastest growing areas of research and its practical applications to derivatives pricing problem. Since the discovery of the famous Black-Scholes equation in the 1970's we have seen a surge in the number of models for a wide range of products such as plain and exotic options, interest rate derivatives, real options and many others. Gone are the days when it was possible to price these derivatives analytically. For most problems we must resort to some kind of approximate method.

In this book we employ partial differential equations (PDE) to describe a range of one-factor and multi-factor derivatives products such as plain European and American options, multi-asset options, Asian options, interest rate options and real options. PDE techniques allow us to create a framework for modeling complex and interesting derivatives products. Having defined the PDE problem we then approximate it using the Finite Difference Method (FDM). This method has been used for many application areas such as fluid dynamics, heat transfer, semiconductor simulation and astrophysics, to name just a few. In this book we apply the same techniques to pricing real-life derivative products. We use both traditional (or well-known) methods as well as a number of advanced schemes that are making their way into the QF literature: Crank-Nicolson, exponentially fitted and higher-order schemes for one-factor and multi-factor options Early exercise features and approximation using front-fixing, penalty and variational methods Modelling stochastic volatility models using Splitting methods Critique of ADI and Crank-Nicolson schemes; when they work and when they don't work Modelling jumps using Partial Integro Differential Equations (PIDE) Free and moving boundary value problems in QF

Included with the book is a CD containing information on how to set up FDM algorithms, how to map these algorithms to C++ as well as several working programs for one-factor and two-factor models. We also provide source code so that you can customize the applications to suit your own needs.

Organizations such as the Sierra Club and Friends of the Earth are familiar to anyone with an interest in environmental protection. As activist groups, they played by the same rules for years. But in 1994, the rules changed.

With the Republican takeover of Congress, environmental groups faced sweeping changes in federal policies that threatened the enforcement of environmental laws. As these organizations intensified their efforts to meet these challenges, they also altered their electoral strategies and political spending patterns. This book traces those actions and shows what they mean for the future of environmentalism in the political arena.

While environmental advocacy groups have become bigger and better funded in recent years, so have the corporate interests that compete with them for the attention of public and politicians. The Green Agenda in American Politics offers a new look at environmental advocacy that focuses on contemporary lobbying, electioneering, and agenda setting in this new context.

Drawing on interviews with activists from a wide range of organizations, Robert Duffy describes what environmental groups actually do when lobbying officials or the public. He examines activity at both national and state levels to emphasize their growing use of websites, email, and action alert networks to conduct more sophisticated grassroots campaigns, and he shows how they are devoting more funds to unregulated forms of spending such as independent expenditure, issue advocacy advertising, and public education campaigns.

Duffy also tracks emerging trends in interest group politics and provides an overview of activism through the early 1990s. He then documents the emergence of more aggressive action after 1994, such as providing campaign services to candidates and mounting voter registration drives. He also shows how state and local groups have begun to play more important roles in the wake of the rollback of federal environmental regulations.

Brimming with new insights into interest group lobbies in general and contemporary environmental groups in particular, Duffy's book opens a new window on the influence of Big Money in the supposedly democratic electoral process.

Chromosome 23 is about you and me, all of us. It is the soupmix of life, the story of "XX" and "XY" chromosome, the female and the male. You will understand the relationship of man and woman once you understand the design of Chromosome 23. You will have new understanding, insights and abilities when interacting with the opposite sex.

Few people volunteer to write, review or pass judgement on Business Cases in the Information Technology sector. Even fewer actually enjoy it. Too much mystery about where to start, what to cover and how to say it. With "Demystifying Business Cases for Information Technology, GIS and more" we see that it can be much easier than we think and we can be much more effective than we ever thought possible. Read about Duffy's Nine Step Model and ideas about content, format and so many tips on how to structure the case and its narrative. This is a light and personable delivery of a lesser known business imperative and reads like you are being spoken to directly, like a story being read. This book is ideal for anyone involved in the analysis, management or planning for IT in all its forms including GIS (geographic information systems), CRM (customer relationship management), ERP (enterprise resource planning), BI (business intelligence), SCM (supply chain management), PPM (project portfolio management) and so much more ... because the basics apply everywhere. The Demystifying messages of 'how-to-write" are fully adaptable to corporate templates and prescribed methods of "what-to-write." Read it once to become aware of the ideas and concepts. Read it again soon after to apply your added knowledge and to corporate nuances to the Nine Steps. Then use the book as a reference when you next write, review or contribute to an IT business case.

The Battle for "Charlie" took place in 1972 during the Vietnam War after most American troops had been withdrawn. A battalion of South Vietnamese paratroopers made a stand reminiscent of the Spartans at Thermopylae in 480 BC. The heroic ARVN troops fought with a single American advisor-Major John J. Duffy, who directed critical American air support and the breakout. Thousands of North Vietnamese Army (NVA) troops invaded the South with overwhelming ground combat strength, supported by long-range artillery and tanks. They were part of a force ordered to conquer the South by cutting it in half. In the Central Highlands, the 11th Airborne Battalion was flown to a mountain pass designated "Charlie" and ordered to block the large NVA force at all costs. Two weeks of vicious close-range fighting ended with both sides suffering horrific casualties. The greatly outnumbered ARVN paratroopers fought until 90% of their comrades were dead or disabled. The enemy death toll exceeded 1,000 and caused a two-week delay in the invasion timetable. This setback in their strategy caused the overall invasion to fail and forced an NVA withdrawal. Victory was won at great cost. Only 37 of the 471 paratroopers escaped the encirclement. Major Duffy was wounded several times while controlling critical air support throughout the battle. Because he had the only ground-air radio, he was targeted by the NVA as he planned and led a daring escape through enemy lines and ambushes. Under fire at the jungle landing zone, he was the last man to board the rescue chopper after assisting and confirming all troops were safely aboard. Major Duffy received the Distinguished Service Cross for valor and for saving the lives of the survivors. The story is told with poems, eyewitness accounts, and transcripts of a tape-recording by eyewitness (evacuation helicopter co-pilot).

Darby and his two best friends Jake and Rick are modern day cowboys on a 3 day horse pack trip into the wilderness of southern Utah Mountains. Unforeseen events and the quest for survival force the three young men through the fabric of time into unknown worlds and alien encounters that challenge the very core of whom they are and who they will be as they face apocalyptic events. Darby worries that he will never see his beloved Laura Beth in time to save her from the certain destruction over the horizon.