This book demonstrates that universities are subject to fundamental change, evolving from science-based, monodisciplinary institutions into transfunctional, 'international know-how hubs' named 'third generation universities' or 3GUs. J.G. Wissema explores the combination of forces that propel this dramatic change, tracing the historic development of universities, and exploring the technology-based enterprises, technostarters and financiers for start-ups and young enterprises that are the main partners of these 3GUs. He goes on to illustrate that universities play a new role as incubators of new science- or technology-based enterprises and take an active role in the exploitation of the knowledge they create. The book concludes with suggestions regarding the way in which changes in the university's mission should be reflected in subsequent organisational changes. Offering practical advice on the route forward for universities, and elucidating the role of education in entrepreneurship, this unique book will prove invaluable to academics and practitioners who seek to implement and facilitate changes for 3GU status. It will also appeal to students and researchers with an interest in business and management, education, entrepreneurship and public policy on education.