Yamada s Textbook of Gastroenterology has for 20 years been the most comprehensive gastroenterology reference book, combining an encyclopaedic basic science approach to GI and liver disease with the latest clinical thinking, especially in diagnostic and therapeutic developments. It is universally respected across the globe. The original outstanding editorial team was led by Tadataka Yamada, MD, one of the world's leading figures in GI research. As in previous editions, the new textbook reflects the collective efforts of the editors and a hugely impressive team of contributors, who are each experts in their specific areas. Now with another world leader in gastroenterology as Editor-in-Chief, Daniel K. Podolsky MD, President and Professor of Internal Medicine at the University of Texas Southwestern Medical Center, together with a stellar group of associate editors, the 6th edition of this iconic textbook has been expanded and enhanced in many ways with new content and technology.

The great composer Ludwig van Beethoven often disgraced himself in public (he threw a bowl of hot stew at a waiter), was once arrested and charged with dereliction, and was widely believed to be mad. His clothes were so rumpled and dirty that street urchins would mock him. He had trouble holding on to servants, and what few friends he had, when they came to his flat, had to put up with stench from an unemptied chamber pot that he kept beside his piano. He became deaf. Mysterious ailments further isolated him from human society. Loneliness and desperation leap from the pages of his intimate letters and scribbled entries in his notebooks. He contemplated suicide. His relations with women were troubled and short-lived: at age forty he impulsively proposed marriage to a fifteen year old girl-who rejected him. Other liaisons came to naught. He wrote an opera about conjugal love in which the heroine, Leonora, rescues her husband from a dark cell under a fortress: one suspects this choice of subject reflects the composer's own need to be rescued, the need for such a woman in his own life. But a woman did come into his life-a woman different from all the others. After his death a few friends discovered a small compartment in his writing desk secured by a bent nail. In it was a three part love letter that he wrote to a woman who claimed that she loved him; he called her his immortal beloved. We have long wondered who this woman is. We now believe she is Antonie Brentano. What took place between these lovers? Mr. Gregory's novel explores the fears and doubts that must have afflicted the great composer as the star-crossed lovers come together in a locked embrace.

The West and China Since 1500 surveys Western relations with and attitudes toward China since sustained contact and desirable trading began with the great alternative culture in the 16th century. The experiences of traders, diplomats, and missionaries are surveyed and illustrated by frequent quotations from contemporary sources. In addition the book explores the flow of cultural influences in both directions, and changes in Western opinion about China from admired model, to disdained "land of the eternal standstill," to feared resurgent power. Finally, the author examines current issues in dispute such as Taiwan and human rights.

A thoroughly updated and expanded edition of the xVA challenge The period since the global financial crisis has seen a major re-appraisal of derivatives valuation, generally expressed in the form of valuation adjustments ('xVAs'). The quantification of xVA is now seen as fundamental to derivatives pricing and valuation. The xVA topic has been complicated and further broadened by accounting standards and regulation. All users of derivatives need to have a good understanding of the implications of xVA. The pricing and valuation of the different xVA terms has become a much studied topic and many aspects are in constant debate both in industry and academia. Discussing counterparty credit risk in detail, including the many risk mitigants, and how this leads to the different xVA terms Explains why banks have undertaken a dramatic reappraisal of the assumptions they make when pricing, valuing and managing derivatives Covers what the industry generally means by xVA and how it is used by banks, financial institutions and end-users of derivatives Explains all of the underlying regulatory capital (e.g. SA-CCR, SA-CVA) and liquidity requirements (NSFR and LCR) and their impact on xVA Underscores why banks have realised the significant impact that funding costs, collateral effects and capital charges have on valuation Explains how the evolution of accounting standards to cover CVA, DVA, FVA and potentially other valuation adjustments Explains all of the valuation adjustments - CVA, DVA, FVA, ColVA, MVA and KVA - in detail and how they fit together Covers quantification of xVA terms by discussing modelling and implementation aspects. Taking into account the nature of the underlying market dynamics and new regulatory environment, this book brings readers up to speed on the latest developments on the topic.

This book, first published in 1982, collects together a wide range of Western reportage on this major revolt in nineteenth century China. The extracts are contemporary, from eyewitnesses, and come from diplomatic and missionary reports, from books, newspapers, private journals, travel accounts and diaries. They provide a good overview of the response to this major crisis of Chinese society over a twenty-year period and the Western presence in mid-nineteenth century China.

This volume brings together academic economists and lawyers to evaluate and compare the regulation of telecommunications markets in Germany and the United States. The unifying theme in all of the pa pers is that the goal of public policy in this area should be to make the broadest and most functional competition possible by means of an ap propriate regulatory framework. Because the European and American telecommunications markets are becoming more intertwined each day, the issues addressed in this volume will be topical to the business, government, and academic communities for some time. For the chairman of the Monopoly Commission, Wernhard Moschel, the opening of the German telecommunications market has been successful in principle. This is clearly recognizable in the case of the competition in long-distance transport. Based on the view that the regulatory authority should make itself obsolete, Professor Moschel advocates an incremental review and gradual reduction of regulation."

This book, first published in 1982, collects together a wide range of Western reportage on this major revolt in nineteenth century China. The extracts are contemporary, from eyewitnesses, and come from diplomatic and missionary reports, from books, newspapers, private journals, travel accounts and diaries. They provide a good overview of the response to this major crisis of Chinese society over a twenty-year period and the Western presence in mid-nineteenth century China.

This text brings together academics, lawyers, trade unionists and industrial relations experts from three continents to provide an analysis of the impact of globalization and deregulation on gender inequality in employment. It reviews the evolution of pay equity policies, examines the impact of economic and social trends on divisions between women and includes detailed analysis of equal pay legislation in the UK.

"These books present a comprehensive coverage of issues facing wheat production globally. The authors represent the top scientists involved in the diverse areas that are important for sustainable wheat production and will this book provides an excellent resource for those interested in wheat improvement and production." Dr Hans-Joachim Braun, Director Global Wheat Program and CRP Wheat, International Maize and Wheat Improvement Center (CIMMYT), Mexico Wheat is the most widely cultivated cereal in the world and a staple food for around 3 billion people. It has been estimated that demand for wheat could increase by up to 60% by 2050. There is an urgent need to increase yields in the face of such challenges as climate change, threats from pests and diseases and the need to make cultivation more resource-efficient and sustainable. Drawing on an international range of expertise, this collection focuses on ways of improving the cultivation of wheat at each step in the value chain, from breeding to post-harvest storage. Volume 2 reviews research in improving cultivation techniques. Chapters in Part 1 review topics such as variety selection, seed and root growth, water and nutrient management. Part 2 goes on to discuss broader issues such as sustainable intensification and organic cultivation. The final part of the collection covers ways of improving wheat cultivation in the developing world. Achieving sustainable cultivation of wheat Volume 2: Cultivation techniques will be a standard reference for cereal scientists in universities, government and other research centres and companies involved in wheat cultivation. It is accompanied by Volume 1 which reviews breeding, quality traits, pests and diseases.

The systems movement, now 40 years old, is made up of many associations of systems thinkers from different disciplines all over the world. The United Kingdom Systems Society (UKSS) was formed in 1978. Today it has over 300 members and is committed to the development and promotion of "systems" philosophy, theory, concepts and methodolo gies for improving decision making for the benefit of organizations and wider society. The first UKSS International Conference was held at the University of Hull in July ofHuddersfield 1989. Since then we have held International Conferences at the Universities (1991) and Paisley (1993). The UKSS International Conferences are now an established biannual event and this, our fourth international conference, will be jointly hosted by the Universities of Hull and Humberside. Systems science is considered to be a trans-discipline which promotes critical and effective intervention in complex organisational and social problem situations. As such it traverses "hard," through "soft" to "critical" systems thinking and methodologies. Yet, despite the currently robust state of the UKSS the systems movement cannot be described as an international movement: different subdisciplines are at different stages of development and are often engaged in pursuing their own particular interests and themes with little "conversation" between the subdisciplines despite their common interest in systems."

This book is suitable for a first year, non-calculus physics course. It covers mechanics, fluids, gravitation, thermal physics, electricity and magnetism, and modern physics, including atoms, an introduction to quantum mechanics, special relativity, and nuclear and particle physics. Trigonometric functions and vectors are introduced as needed.

This 1998 book addresses deregulatory policies that threaten to reduce or destroy the value of private property in network industries without any accompanying payment of just compensation, policies that are termed 'deregulatory takings'. The authors further consider the problem of renegotiation of the regulatory contract, which changes the terms and conditions of operation of utility companies. They argue that constitutional protections of private property from takings, as well as efficient remedies for contractual breach, provide the proper foundation for the competitive transformation of the network industries. The benefits of competition do not stem from government regulations that redistribute income from utility investors to customers, nor do such benefits stem from regulatory policies for network access that promote free riding on incumbent facilities by entrants. Such actions represent a new version of increased regulation, not deregulation.

This new edition revisits the major issues affecting individuals with mental retardation, those personally responsible for their education and well being, and society at large. The text provides up-to-date material on the major dimensions of the disorder - its nature, its causes, and its treatment or management. New topics covered include causation, diagnosis, and treatment of severe maladaptive behaviour disorders observed in mental retardation, including problematic sexual behaviours, and behaviour that is classifiable in terms of formal psychiatric syndromes. In addition, the revised text includes discussion questions at the end of each chapter, and boxed material and appendixes to supplement the content.