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This book traces the endeavor in U.S. to develop a means of
protecting the people from the effects of nuclear war. It shows how
the policies that have emerged are as much products of the
political process as of weapons technology.
To many, civil defense stands as a symbol of the futility of
society's attempt to escape the consequences of its own creations.
Unlike other areas of national security policy, civil defense has
never attracted widespread support and has encountered constant
difficulties in securing political and financial backing. In
addition, rapidly evolving military technology has consistently
eroded the substance of the program and its credibility in the eyes
of the public. This book traces the continuing endeavor in the
United States to develop a means of protecting the American people
from the effects of nuclear war. It is a story of frustration and,
to a large degree, failure. The book begins with the pre-nuclear
period of the two world wars, when political and organizational
precedents were established that served as the basis for the Civil
Defense Act of 1950. It then recounts the evolution of civil
defense practices from the early 1950s to the present, during which
time attention was focused, in tum, upon blast shelters,
evacuation, fallout shelters, and, currently, crisis relocation.
Dr. Kerr shows how the policies that have emerged are as much
products of the political process as of weapons technology-how they
reflect specific interactions between Congress and the executive
branch in an environment marked by apathy on the part of the
general public and hostility on the part of articulate groups.
Here in a single source is a complete spectrum of ideas on the
development of new anticancer drugs. Containing concise reviews of
multidisciplinary fields of research, this book offers a wealth of
ideas on current and future molecular targets for drug design,
including signal transduction, the cell division cycle, and
programmed cell death. Detailed descriptions of sources for new
drugs and methods for testing and clinical trial design are also
provided.
KEY FEATURES:
* One work that can be consulted for all aspects of anticancer drug
development
* Concise reviews of research fields, combined with practical
scientific detail, written by internationally respected
experts
* A wealth of ideas on current and future molecular targets for
drug design, including signal transduction, the cell division
cycle, and programmed cell death
* Detailed descriptions of the sources of new anticancer drugs,
including combinatorial chemistry, phage display, and natural
products
* Discussion of how new drugs can be tested in preclinical systems,
including the latest technology of robotic assay systems, cell
culture, and experimental animal techniques
* Hundreds of references that allow the reader to access relevant
scientific and medical literature
* Clear illustrations, some in color, that provide both
understanding of the field and material for teaching
Today's economy is rapidly shifting and extremely complex. As we
enter this new commercial age, a global restructuring of the
business world is underway. Executives must respond to this change
by re-imagining their organizations' structures, enhancing product
and service offerings, and leveraging emerging technological
capabilities in order to keep their organizations vital for years
to come.
Written for executives and those aspiring to become one, this book
serves as a primer for how to set direction and manage change
within the 21stcentury enterprise. Organized into easily accessible
checklists, each chapter demystifies a key aspect of today's
leadership challenge and outlines the steps necessary to revitalize
today's businesses. The 'See It In Action' sidebars provide real
world examples of how these concepts are already being implemented
in businesses today, featuring companies such as CIGNA HealthCare,
Forbes Insights, Virgin Records, DreamWorks Animation, Google,
Molex, and Marriott International. Together, these chapter
checklists encompass a guide that can be used to institute an
overarching, enterprise-wide transformation program and make
today's ultra-complex business world a little easier to
manage.
Analyzing Intelligence, now in a revised and extensively updated
second edition, assesses the state of the profession of
intelligence analysis from the practitioners point of view. The
contributors-most of whom have held senior positions in the US
intelligence community-review the evolution of the field, the rise
of new challenges, pitfalls in analysis, and the lessons from new
training and techniques designed to deal with 21st century national
security problems. This second edition updates this indispensable
book with new chapters that highlight advances in applying more
analytic rigor to analysis, along with expertise-building,
training, and professional development. New chapters by
practitioners broaden the original volume's discussion of the
analyst-policymaker relationship by addressing analytic support to
the military customer as well as by demonstrating how structured
analysis can benefit military commanders on the battlefield.
Analyzing Intelligence is written for national security
practitioners such as producers and users of intelligence, as well
as for scholars and students seeking to understand the nature and
role of intelligence analysis, its strengths and weaknesses, and
steps that can improve it and lead it to a more recognizable
profession. The most comprehensive and up-to-date volume on
professional intelligence analysis as practiced in the US
Government, Analyzing Intelligence is essential reading for
practitioners and users of intelligence analysis, as well as for
students and scholars in security studies and related fields.
The United States has not elected a woman President in 238 years.
Mr. Kerr has written a fictional novel about the first woman
President. He delves into the atmosphere in Washington and many of
the domestic issues. And, there is a scandal and a terrorist
threat. Welcome to Washington, Madam President.
Substance abuse is one of society's most serious problems. Drugs
seem to be readily available in virtually every country in the
world. Substance abuse is the overindulgence in and dependence of a
drug or other chemical leading to effects that are detrimental to
the individual's physical and mental health, or the welfare of
others. The disorder is characterised by a pattern of continued
pathological use of a medication, non-medically indicated drug or
toxin, that results in repeated adverse social consequences related
to drug use, such as failure to meet work, family, or school
obligations, interpersonal conflicts, or legal problems. There are
on-going debates as to the exact distinctions between substance
abuse and substance dependence, but current practice standard
distinguishes between the two by defining substance dependence in
terms of physiological and behavioural symptoms of substance use,
and substance abuse in terms of the social consequences of
substance use. This book presents the latest research in the field.
The former Jewel in the Crown of the British Empire, India remains,
by any measure, a major economic and political actor on the world
scene. Without her extensive railway network—completed against
all odds by her British colonial masters—it is impossible to
imagine what might have become of the diverse lands and peoples of
the subcontinent. These railway networks brought them together as a
colony; these networks fostered the nationalism that would be
Britain's downfall. This rail network both remade the physical
landscape and brought social-cultural cohesion to a diverse and
wide-ranging populace. It would be common rail travel that Gandhi
would employ to reach the masses. From its romantic mystique to its
dangerous reality, it is rail travel today that keeps vital social,
cultural, economic and political forces moving. India's railroad
history serves as a unique lens to her larger story of triumph over
adversity. By 1905, India had the world's fourth largest railway
network—a position it retains in the early 21st century. The
railroads were at the organizational and technological center of
many of the inter-related economic, political, social, cultural,
and ecological transformations that produced modern India through,
and out of, its colonial past. In addition to this vast technical
achievement, and (in keeping with the series focus), there is an
equally important and wide-sweeping human-interest tale to be told
with evocative vignettes of the triumph of the human spirit (one
billion strong!) in the face of great adversity.
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