An original and energetic examination of the relationship between theology, faith, religious history and national politics in the works of Oscar Wilde, which focuses in particular on his life-long attraction to Catholicism. Wilde's Protestant heritage is also scrutinized, and its continued influence on him, as well as his antagonism towards it, is related to the narrative modes he chose and the philosophical positions he adopted.

Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape.Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to improve the predictive power of today's drug safety tests.Fundamental to addressing the problem of drug-induced arrhythmias, and to reducing the impact of this safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and what opportunities there are to enhance patient safety and reduce the risk of detecting cardiac toxicity in later stages of product commercialization. By introducing the reader to these core concepts, this book delivers key insight into the increasingly important and dynamic field of cardiac safety.

Because magnetically confined plasmas are generally not found in a state of thermodynamic equilibrium, they have been studied extensively with methods of applied kinetic theory. In closed magnetic field line confinement devices such as the tokamak, non-Maxwellian distortions usually occur as a result of auxiliary heating and transport. In magnetic mirror configurations even the intended steady state plasma is far from local thermodynamic equilibrium because of losses along open magnetic field lines. In both of these major fusion devices, kinetic models based on the Boltzmann equation with Fokker-Planck collision terms have been successful in representing plasma behavior. The heating of plasmas by energetic neutral beams or microwaves, the production and thermalization of a-particles in thermonuclear reactor plasmas, the study of runaway electrons in tokamaks, and the performance of two-energy compo nent fusion reactors are some examples of processes in which the solution of kinetic equations is appropriate and, moreover, generally necessary for an understanding of the plasma dynamics. Ultimately, the problem is to solve a nonlinear partial differential equation for the distribution function of each charged plasma species in terms of six phase space variables and time. The dimensionality of the problem may be reduced through imposing certain symmetry conditions. For example, fewer spatial dimensions are needed if either the magnetic field is taken to be uniform or the magnetic field inhomogeneity enters principally through its variation along the direction of the field."

An original and energetic examination of the relationship between theology, faith, religious history and national politics in the works of Oscar Wilde, which focuses in particular on his life-long attraction to Catholicism. Wilde's Protestant heritage is also scrutinised, and its continued influence on him, as well as his antagonism towards it, is related to the narrative modes he chose and the philosophical positions he adopted.

A detailed look at the expansion and renewal taking place on the three U of I campuses The University of Illinois System’s universities have undergone a dramatic transformation. This lavishly illustrated volume showcases the major capital projects and renovations dedicated to keeping facilities on the cutting edge while at the same time preserving history at the universities in Urbana-Champaign, Chicago, and Springfield. Fueled by an ambitious capital initiative launched in 2018, these essential and forward-looking changes include more than 500 projects valued at $4 billion over 10 years. The initiative harnesses a mix of innovative funding programs like public-private partnerships, thoughtful use of capital reserves and bonding authority, and generous state funding. Covering completed and ongoing projects, Building Momentum offers a one- or two-page feature on each undertaking that covers its history and purpose while providing specific details about its unit, campus, architect, square footage or renovation size, budget, and LEED or other certifications. More than 100 architectural drawings and commissioned and historical photographs round out the descriptions.

Global society is once again focusing its attention on the Amazon, but the outlook is bleak. Top-down approaches that depend on macroeconomic policies are not changing the behaviour of the inhabitants of the forest frontier. Efforts to improve law enforcement have failed because frontier societies are profoundly unequal; inequality encourages informality, breeding corruption and illegality. Indigenous people have stepped into the breach and are doing what they can to stave off disaster, but they are vastly outnumbered. Most inhabitants - who are also citizens that vote - pursue conventional production models that are fundamentally non-sustainable. They might choose different pathways, given the opportunity, but these are limited by the frontier economy and the social reality of their communities. We are losing the Amazon. Volume One of Tim Killeen's serial monograph delivers an unvarnished description of the obstacles to conserving the world's largest and most important tropical forest. Chapter One starts with a lucid narrative of the complex and interrelated social and economic forces driving deforestation, with a critical review of policy initiatives designed to change that trajectory towards a more sustainable future. Chapters Two (Infrastructure), Three (Agriculture) and Four (Land) lay bare the history, economics and business models that underpin the conventional economy. Two further volumes will address other key aspects of a sustainable future, including: the extractive sector (Ch. 5); the culture wars that divide the populace (Ch. 6); evolving governance systems (Ch. 7); the potential of the forest economy (Ch. 8); advances in biodiversity science (Ch. 9); the looming impact of climate change (Ch.10); the indigenous awakening (Ch.11); conservation policy (Ch.12); and, finally, the future (Ch.13). Killeen's enormously ambitious effort seeks to understand and explain all the complex and interrelated phenomena driving (and impeding) change across the region. If you are concerned about the fate of the Amazon, you must read this book.

Parque Nacional Noel Kempff Mercado, located in eastern Bolivia where the moist forests of the Amazon meet the dry forests of the Cerrado, contains numerous unique ecosystems and exceptionally high levels of biodiversity. This book presents the results not only of an intensive biological survey of the area conducted in 1991, but also of long-term research conducted from 1987 to 1995. Among other findings, the survey discovered 26 new species of plants, one new mammal species, and three new species of reptiles.
This report, with text in both English and Spanish, includes extensive data appendices, a large fold-out satellite map of vegetation, and conservation recommendations for the region.