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Microbial biofilms: Role in Human Infectious Diseases focuses on
new and emerging concepts in microbial biofilm research, such as
the mechanisms of biofilm formation, biofilm-induced pathogenesis,
biofilm detection/and diagnosis, gene exchange within biofilms,
strategies to control microbial biofilms and the burden of biofilm
associated infections. In addition, it highlights the various
anti-biofilm strategies such as surface coating, signal quenching,
novel compounds that can be translated to curb biofilm-associated
infections and the escalation of antimicrobial resistance
determinants. Microbial biofilms can be a serious problem in
medical settings as they are associated with significant mortality
and morbidity. Infection related to biofilms increases recovery
time and the cost of disease management. Biofilms are resistant to
known antibiotics and human defense mechanism. In addition, due to
close proximity of microbes within biofilms, increase genetic
transformation has been detected results in increases frequency of
antibiotic gene spread. With the advancement in science and
technology, novel strategies have been proposed to combat the
impact of biofilms on human health.
Nanotechnology in Human Health: Current Research and Future Trends
details the various challenges faced in human healthcare settings
and how nanotechnology can be used to target and improve outcomes.
The book describes the application of nanoparticles in the
diagnosis of human diseases, including metabolic diseases, cancer,
bacterial infection, organ degeneration and the various targeted,
nano-based treatments available. Several chapters look at how
microbial biofilms - a key clinical concern - can be mitigated
using nanomaterials and nanotechnology. In addition, the book
covers how different nanoparticle types can be utilized as
therapeutic agents. This book combines materials science concepts
and techniques with clinical insights and understanding to provide
an interdisciplinary reference for materials scientists,
microbiologists, biomedical engineers and clinicians with an
interest in nanotechnology.
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