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This volume presents key topics of current interest with regard to
several pathophysiological conditions including (a) the basic and
clinical aspects of bradykinin receptor antagonists, (b) the
kallikrein-kinin pathways in hypertension and diabetes, (c) tissue
kallikrein-kinin therapy for hypertension and organ damage, (d) the
renal (tissue) kallikrein-kinin system in the kidney and novel
potential drugs for salt-sensitive hypertension, (e) the
kallikrein-kinin system in diabetes retinopathy, and (f) genetic
manipulation and genetic variation of the kallikrein-kinin system
and their impacts on cardiovascular and renal disease. Written by
internationally reputed scientists, the book provides an essential
overview of the latest developments in the field of kinin research,
making it a valuable asset for endocrinologists, nephrologists,
cardiologists, pharmacologists, physiologists, ophthalmologists and
rheumatologists. Furthermore, it is also intended for postgraduate
students in the fields of medicine, pharmacy, physiology and
pharmacology, and those working at research organizations.
This volume presents key topics of current interest with regard
to several pathophysiological conditions including (a) the basic
and clinical aspects of bradykinin receptor antagonists, (b) the
kallikrein-kinin pathways in hypertension and diabetes, (c) tissue
kallikrein-kinin therapy for hypertension and organ damage, (d) the
renal (tissue) kallikrein-kinin system in the kidney and novel
potential drugs for salt-sensitive hypertension, (e) the
kallikrein-kinin system in diabetes retinopathy and (f) genetic
manipulation and genetic variation of the kallikrein-kinin system
and their impacts on cardiovascular and renal disease. Written by
internationally reputed scientists, the book provides an essential
overview of the latest developments in the field of kinin research,
making it a valuable asset for endocrinologists, nephrologists,
cardiologists, pharmacologists, physiologists, ophthalmologists and
rheumatologists. Furthermore, it is also intended for postgraduate
students in the fields of medicine, pharmacy, physiology and
pharmacology and those working at research organizations.
Pharmacology can be defined as a discipline of paramedical sciences
that teaches how the use of drugs can bring about changes from
pathological states to physiological conditions. Whereas mediator
pharmacology is a subdivision pharmacology which teaches the
functions of molecules released in the body and produces profound
pharmacological effects. Also, their sustained release may results
in pathological conditions. The agonists or antagonists of these
mediators may offer novel therapeutic agents for clinical benefits.
This book provides necessary scientific developments in mediator
pharmacology.
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