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A distinguished international panel of authors define our current
understanding of neuronal damage after ischemia and critically
review the significant recent developments and progress in
cerebrovascular accident (CVA) drug trials, both in animal models
and in the clinical setting. These leading basic and fundamental
authorities survey such important new drugs as calcium-influx
inhibitors, free-radical scavenging drugs, glutamate and
glycinergic antagonists, and immune suppressors. They also evaluate
all the latest findings concerning calcium homeostasis, glutamate
toxicity, gene activation, and the role of free radicals, glycine,
and hormones. Chapters devoted to the neuroimaging of stroke,
clinical trials, and the role of cerebral immune activation
complete this informative collection of cutting-edge reviews.
In Clinical Pharmacology of Cerebral Ischemia, a distinguished
international panel of authors define our current understanding of
neuronal damage after ischemia and critically review the
significant recent progress in cerebrovascular accident (CVA) drug
trials, both for animal models and in the clinical setting. These
leading basic science and medical authorities survey such important
new drugs as calcium-influx inhibitors, free-radical scavenging
drugs, glutamate and glycinergic antagonists, and immune
suppressors. They also evaluate all the latest findings concerning
calcium homeostasis, glutamate toxicity, gene activation, and the
role of free radicals, glycine, and hormones. Chapters devoted to
the neuroimaging of stroke, clinical trials, and the role of
cerebral immune activation complete this informative collection of
cutting-edge reviews.
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