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During the period August 5-9, 1992, and immediately preceding the
1992 Gordon Research Conference on Motile and Contractile Systems,
the "Third International Conference on the Structure and Function
of Ubiquitous Cellular Protein Actin" was held at the Emma Willard
School in Troy, New York, under the title "ACTIN '92". This
conference focused on the fundamental properties and cellular
functions of actin and actin based microfilament systems. The first
conference in this series was held in 1982, in Sydney, Australia,
and hosted by Dr. Cristobal G. dos Remedios and Dr. Julian A.
Barden, both from the University of Sydney (New South Wales,
Austrailia). The second conference convened in Monza, Italy in June
1987, and was organized by Dr. Roberto Colombo, University of Milan
(Italy). This third gathering of researchers devoted to the study
of actin and actin-associated proteins was organized by Dr. James
E. Estes, Albany Stratton V A Medical Center and Dr. Paul 1.
Higgins, Albany Medical College, who were assisted by an Organizing
Committee consisting of Dr. Edward D. Korn (National Heart, Lung
and Blood Institute, NIH), Dr. Thomas P. Stossel (Massachusetts
General Hospital), Dr. Fumio Matsumura (Rutgers University), and
Dr. Stephen Farmer (Boston University). This meeting was dedicated
to the many pioneering contributions of Professor Fumio Oosawa to
the field of actin research.
Basic Properties of the Actin Molecule and Actin-Based
Microfilament Systems.- Vibrational Modes of G-Actin.- Combining
Electron Microscopy and X-Ray Crystallography Data to Study the
Structure of F-Actin and its Implications for Thin-Filament
Regulation in Muscle.- Evidence for an F-Actin Like Conformation in
the Actin: DNase I Complex.- Actin-Bound Nucleotide/Divalent Cation
Interactions.- Influence of the High Affinity Divalent Cation on
Actin Tryptophan Fluorescence.- C-Terminus on Actin: Spectroscopic
and Immunochemical Examination of its Role in Actinomycin
Interactions.- Actin Polymerization: Regulation by Divalent Metal
Ion and Nucleotide Binding, ATP Hydrolysis and Binding of Myosin.-
Actin-Associated Proteins and Control of Filament-Based
Assembly-Disassembly.- Structural Requirements of Tropomyosin for
Binding to Filamentous Actin.- Actin-Gelsolin Interaction.- Actin
Regulation and Surface Catalysis.- Caldesmon: Possible Functions in
Microfilament Reorganization During Mitosis and Cell
Transformation.- Cytoskeleton, Motile Structures and Macromolecular
Crowding.- Cellular Functions of the Microfilament System.- Actin
Filament Dynamics in Cell Motility.- Changes in Adhesion Plaque
Protein Levels Regulate Cell Motility and Tumorigenicity.-
Induction of Collagen Synthesis in Response to Adhesion and TGF? is
Dependent on the Actin-Containing Cytoskeleton.- Gelsolin
Expression in Normal Human Keratinocytes is a Function of Induced
Differentiation.- Actin Filaments and the Spatial Positioning of
mRNA.- Redistribution of p52(PAI-l) mRNA to the Cytoskeletal
Framework Accompanies Increased p52(PAI-l) Expression in
Cytochalasin D-Stimulated Rat Kidney Cells.- Brush Border Myosin I
Has a Calmodulin/Phosphatidylserine Switch and Tail Actin-Binding.-
Control of p52(PAI-l) Gene Expression in Normal and Transformed Rat
Kidney Cells: Relationship Between p52(PAI-l) Induction and Actin
Cytoarchitecture.- Contributors
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