Speculative modernists-that is, British and American writers of science fiction, fantasy and horror during the late 19th and early 20th centuries-successfully grappled with the same forces that would drive their better-known literary counterparts to existential despair. Building on the ideas of the 19th-century Gothic and utopian movements, these speculative writers anticipated literary Modernism and blazed alternative literary trails in science, religion, ecology and sociology. Such authors as H.G. Wells and H.P. Lovecraft gained widespread recognition-budding from them, other speculative authors published fascinating tales of individuals trapped in dystopias, of anti-society attitudes, post-apocalyptic worlds and the rapidly expanding knowledge of the limitless universe. This book documents the Gothic and utopian roots of speculative fiction and explores how these authors played a crucial role in shaping the culture of the new century with their darker, more evolved themes.

If you understand how drugs work (pharmacodynamics), how they are handled by the body (pharmacokinetics), how they interact with each other, and how drug treatments are assessed, then you will become a better prescriber. A Textbook of Clinical Pharmacology and Therapeutics gives you that understanding.
Fully revised throughout and extensively illustrated, the fifth edition of this well-established textbook has been streamlined to focus on what medical students and junior doctors really need to know in order to understand the implications of prescribing one drug over, or in combination with, another. The text provides current information on all areas of drug prescribing with updated discussion and guidance on such topics as adverse drug reactions, personalized medicine, gene and cell-based therapy, advances in cancer therapy, and mechanisms of drug action and treatment guidelines in HIV and mycobacterial infections therapy. A new chapter on alternative medicines and nutraceuticals has been introduced and Further Reading lists have been updated to include key medical websites.
All medical students and junior doctors who read this book will learn not only how to use drugs safely and effectively, but, importantly, the rationale behind effective prescribing decisions.

Between the years of 1886 and 1939, the world saw the first automobiles, rapid urbanization, the decay of empires, vast economic inequality, the first airplanes and the terrifying secrets of the atom. It was a time of cataclysmic cultural and technological transformation in both the United States and the United Kingdom, and spawned the rise of the literary genres of science fiction, fantasy and horror. This work assembles gems of late nineteenth and early twentieth century genre literature, including stories by literary giants such as H.P. Lovecraft, Robert E. Howard, C. L. Moore, A. Merritt and E. M. Forster, as well as smaller authors like Clare Winger Harris, Marie Corelli, William Hope Hodgson and others. An array of incisive nonfiction pieces on cultural and scientific advances of the time period provides context for the anthology's stories.