This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.

In this beautifully illustrated and closely argued book, a completely updated and much expanded third edition of his magisterial survey, Curl describes in lively and stimulating prose the numerous revivals of the Egyptian style from Antiquity to the present day. Drawing on a wealth of sources, his pioneering and definitive work analyzes the remarkable and persistent influence of Ancient Egyptian culture on the West.

The author deftly develops his argument that the civilization of Ancient Egypt is central, rather than peripheral, to the development of much of Western architecture, art, design, and religion. Curl examines:

• the persistence of Egyptian motifs in design from Graeco-Roman Antiquity, through the Medieval, Baroque, and Neo-Classical periods
• rise of Egyptology in the nineteenth and twentieth-century manifestations of Egyptianisms prompted by the discovery of Tutankhamun s tomb
• various aspects of Egyptianizing tendencies in the Art Deco style and afterwards.

For students of art, architectural and ancient history, and those interested in western European culture generally, this book will be an inspiring and invaluable addition to the available literature."

Digital Vernacular addresses the why and how of digital fabrication in hundreds of step-by-step color images, illuminating a set of working principles and techniques that join theory with practice. Authors James Stevens and Ralph Nelson reconcile local traditions and innovations with globally accessible methods and digital toolsets. By combining ethics with hardware, the book will root you in the origins of making, ensuring a lasting and relevant reference for your studio practice. The book opens with the origins and principles of the digital vernacular, then outlines digital vernacular tools including computer numerically controlled (CNC) mills, laser cutters, and 3D printers. You'll even learn to create your own digital fabrication tools out of inexpensive materials. The book concludes with the processes of the digital vernacular, including techniques for removing, joining, forming, and adding. A companion website at make-Lab.org hosts additional step-by-step processes and project outcomes.

This beautifully illustrated, closely argued, pioneering, and definitive magisterial survey spans over two thousand years and analyzes the astonishing and persistent influence that Ancient Egyptian culture has had on the West. Professor Stevens Curl describes in lively and stimulating prose the numerous revivals of the Egyptian style from Antiquity to the present day, drawing on a wealth of sources.
The author deftly develops his argument that the civilization of Ancient Egypt is central, rather than peripheral, to the development of much of Western architecture, art, design, and religion. He charts the remarkable persistence of Egyptian motifs in design from Graeco-Roman Antiquity, through the Mediaeval, Baroque, and Neo-Classical periods, and goes on to trace the rise of Egyptology in the nineteenth century, twentieth-century manifestations of Egyptianisms prompted by the discovery of Tutankhamun's tomb, and various aspects of Egyptianising tendencies in the Art Deco style and afterwards.
For students of art, architectural and ancient history, and those interested in Western European culture generally, this book will be an inspiring and invaluable addition to the available literature.

Paul Bunyan (1925) is a novel by James Stevens. Written from a lifetime of experience as a logger and historian of the logging industry, Paul Bunyan is a masterful take on one of the defining legends of the Pacific Northwest. Combining his own stories with those he heard at logging camps as a young boy, Stevens earned a reputation as a leading folklorist of his time whose novels and songs continue to resonate decades after his death. "He could whip his weight in wildcats, could pull clouds out of the sky, or chew up stones, or tell the whole world anything!" Larger than life, Paul Bunyan is a logger whose legend began with the Papineau Rebellion of 1837. As a defender of young Queen Victoria's right to the forests of Canada, Bunyan fought fiercely against French loggers alongside his comrades armed with mattocks, axes, and hooks. Emerging victorious, he settles down to a life in nature, building his logging camp and roaming the woods with his trusted blue ox Babe. From his boyhood in the lumber camps of Idaho to his time as a logger in Oregon, James Stevens collected the tales of Bunyan from the more experienced men of the woods, eventually becoming the foremost expert on one of the Pacific Northwest's greatest heroes. With a beautifully designed cover and professionally typeset manuscript, this edition of James Stevens' Paul Bunyan is a classic work of American literature reimagined for modern readers.

Paul Bunyan (1925) is a novel by James Stevens. Written from a lifetime of experience as a logger and historian of the logging industry, Paul Bunyan is a masterful take on one of the defining legends of the Pacific Northwest. Combining his own stories with those he heard at logging camps as a young boy, Stevens earned a reputation as a leading folklorist of his time whose novels and songs continue to resonate decades after his death. "He could whip his weight in wildcats, could pull clouds out of the sky, or chew up stones, or tell the whole world anything!" Larger than life, Paul Bunyan is a logger whose legend began with the Papineau Rebellion of 1837. As a defender of young Queen Victoria's right to the forests of Canada, Bunyan fought fiercely against French loggers alongside his comrades armed with mattocks, axes, and hooks. Emerging victorious, he settles down to a life in nature, building his logging camp and roaming the woods with his trusted blue ox Babe. From his boyhood in the lumber camps of Idaho to his time as a logger in Oregon, James Stevens collected the tales of Bunyan from the more experienced men of the woods, eventually becoming the foremost expert on one of the Pacific Northwest's greatest heroes. With a beautifully designed cover and professionally typeset manuscript, this edition of James Stevens' Paul Bunyan is a classic work of American literature reimagined for modern readers.

Digital Vernacular addresses the why and how of digital fabrication in hundreds of step-by-step color images, illuminating a set of working principles and techniques that join theory with practice. Authors James Stevens and Ralph Nelson reconcile local traditions and innovations with globally accessible methods and digital toolsets. By combining ethics with hardware, the book will root you in the origins of making, ensuring a lasting and relevant reference for your studio practice. The book opens with the origins and principles of the digital vernacular, then outlines digital vernacular tools including computer numerically controlled (CNC) mills, laser cutters, and 3D printers. You'll even learn to create your own digital fabrication tools out of inexpensive materials. The book concludes with the processes of the digital vernacular, including techniques for removing, joining, forming, and adding. A companion website at make-Lab.org hosts additional step-by-step processes and project outcomes.

The study of architecture requires not only an understanding of the history of buildings, but also knowledge of the correct terminology that is used to describe them. The "Encyclopaedia of Architectural Terms" provides a comprehensive, clearly written, practical guide to the terminology used in the various aspects of architecture and building. It contains over 3500 terms offering definitions of styles, the components of buildings, materials, the various parts of orders and architectural details.

This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.

Ammon's job was simple, to care for the dragon eggs in the Nest. It should have been easy, but it wasn't. When the sun rose after the hatch, he had made an enemy of the most powerful man in the kingdom, and he would soon learn that was the least of his problems

Victorian churches were often of high quality, reflecting in physical terms the intense theological debates of the time. This highly-illustrated book by a leading authority describes many of the finest examples. Many churches were built in England during the reign of Queen Victoria: most were in various varieties of Gothic Revival. Often exquisitely furnished, they were visible expressions of the presence and importance of religion at the time. Their architectural qualities reflected aspirations of clergy, laity, and individual benefactors. The finest were the results of passionate commitment to an architecture soundly based on scholarly studies known as Ecclesiology. James Stevens Curl places English churches of the period in their complex social and denominational settings, giving comprehensive accounts of the religious atmosphere and controversies of the times. He charts the progress and development of the Gothic Revival, explains differences in the architecture of various denominations, outlines the influences of the chief protagonists involved, and describes the demands made on craftsmen and industry to produce the materials, furnishings, and fittings necessary in making some of the finest buildings ever created in England. He reveals something of the individuals and events that shaped the religious climate of the epoch, while specially commissioned illustrations reveal the rich variety found in Victorian churches.