This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.

Digital Vernacular addresses the why and how of digital fabrication in hundreds of step-by-step color images, illuminating a set of working principles and techniques that join theory with practice. Authors James Stevens and Ralph Nelson reconcile local traditions and innovations with globally accessible methods and digital toolsets. By combining ethics with hardware, the book will root you in the origins of making, ensuring a lasting and relevant reference for your studio practice. The book opens with the origins and principles of the digital vernacular, then outlines digital vernacular tools including computer numerically controlled (CNC) mills, laser cutters, and 3D printers. You'll even learn to create your own digital fabrication tools out of inexpensive materials. The book concludes with the processes of the digital vernacular, including techniques for removing, joining, forming, and adding. A companion website at make-Lab.org hosts additional step-by-step processes and project outcomes.

In this beautifully illustrated and closely argued book, a completely updated and much expanded third edition of his magisterial survey, Curl describes in lively and stimulating prose the numerous revivals of the Egyptian style from Antiquity to the present day. Drawing on a wealth of sources, his pioneering and definitive work analyzes the remarkable and persistent influence of Ancient Egyptian culture on the West.

The author deftly develops his argument that the civilization of Ancient Egypt is central, rather than peripheral, to the development of much of Western architecture, art, design, and religion. Curl examines:

• the persistence of Egyptian motifs in design from Graeco-Roman Antiquity, through the Medieval, Baroque, and Neo-Classical periods
• rise of Egyptology in the nineteenth and twentieth-century manifestations of Egyptianisms prompted by the discovery of Tutankhamun s tomb
• various aspects of Egyptianizing tendencies in the Art Deco style and afterwards.

For students of art, architectural and ancient history, and those interested in western European culture generally, this book will be an inspiring and invaluable addition to the available literature."

This beautifully illustrated, closely argued, pioneering, and definitive magisterial survey spans over two thousand years and analyzes the astonishing and persistent influence that Ancient Egyptian culture has had on the West. Professor Stevens Curl describes in lively and stimulating prose the numerous revivals of the Egyptian style from Antiquity to the present day, drawing on a wealth of sources.
The author deftly develops his argument that the civilization of Ancient Egypt is central, rather than peripheral, to the development of much of Western architecture, art, design, and religion. He charts the remarkable persistence of Egyptian motifs in design from Graeco-Roman Antiquity, through the Mediaeval, Baroque, and Neo-Classical periods, and goes on to trace the rise of Egyptology in the nineteenth century, twentieth-century manifestations of Egyptianisms prompted by the discovery of Tutankhamun's tomb, and various aspects of Egyptianising tendencies in the Art Deco style and afterwards.
For students of art, architectural and ancient history, and those interested in Western European culture generally, this book will be an inspiring and invaluable addition to the available literature.

Paul Bunyan (1925) is a novel by James Stevens. Written from a lifetime of experience as a logger and historian of the logging industry, Paul Bunyan is a masterful take on one of the defining legends of the Pacific Northwest. Combining his own stories with those he heard at logging camps as a young boy, Stevens earned a reputation as a leading folklorist of his time whose novels and songs continue to resonate decades after his death. "He could whip his weight in wildcats, could pull clouds out of the sky, or chew up stones, or tell the whole world anything!" Larger than life, Paul Bunyan is a logger whose legend began with the Papineau Rebellion of 1837. As a defender of young Queen Victoria's right to the forests of Canada, Bunyan fought fiercely against French loggers alongside his comrades armed with mattocks, axes, and hooks. Emerging victorious, he settles down to a life in nature, building his logging camp and roaming the woods with his trusted blue ox Babe. From his boyhood in the lumber camps of Idaho to his time as a logger in Oregon, James Stevens collected the tales of Bunyan from the more experienced men of the woods, eventually becoming the foremost expert on one of the Pacific Northwest's greatest heroes. With a beautifully designed cover and professionally typeset manuscript, this edition of James Stevens' Paul Bunyan is a classic work of American literature reimagined for modern readers.

Paul Bunyan (1925) is a novel by James Stevens. Written from a lifetime of experience as a logger and historian of the logging industry, Paul Bunyan is a masterful take on one of the defining legends of the Pacific Northwest. Combining his own stories with those he heard at logging camps as a young boy, Stevens earned a reputation as a leading folklorist of his time whose novels and songs continue to resonate decades after his death. "He could whip his weight in wildcats, could pull clouds out of the sky, or chew up stones, or tell the whole world anything!" Larger than life, Paul Bunyan is a logger whose legend began with the Papineau Rebellion of 1837. As a defender of young Queen Victoria's right to the forests of Canada, Bunyan fought fiercely against French loggers alongside his comrades armed with mattocks, axes, and hooks. Emerging victorious, he settles down to a life in nature, building his logging camp and roaming the woods with his trusted blue ox Babe. From his boyhood in the lumber camps of Idaho to his time as a logger in Oregon, James Stevens collected the tales of Bunyan from the more experienced men of the woods, eventually becoming the foremost expert on one of the Pacific Northwest's greatest heroes. With a beautifully designed cover and professionally typeset manuscript, this edition of James Stevens' Paul Bunyan is a classic work of American literature reimagined for modern readers.

Digital Vernacular addresses the why and how of digital fabrication in hundreds of step-by-step color images, illuminating a set of working principles and techniques that join theory with practice. Authors James Stevens and Ralph Nelson reconcile local traditions and innovations with globally accessible methods and digital toolsets. By combining ethics with hardware, the book will root you in the origins of making, ensuring a lasting and relevant reference for your studio practice. The book opens with the origins and principles of the digital vernacular, then outlines digital vernacular tools including computer numerically controlled (CNC) mills, laser cutters, and 3D printers. You'll even learn to create your own digital fabrication tools out of inexpensive materials. The book concludes with the processes of the digital vernacular, including techniques for removing, joining, forming, and adding. A companion website at make-Lab.org hosts additional step-by-step processes and project outcomes.

The study of architecture requires not only an understanding of the history of buildings, but also knowledge of the correct terminology that is used to describe them. The "Encyclopaedia of Architectural Terms" provides a comprehensive, clearly written, practical guide to the terminology used in the various aspects of architecture and building. It contains over 3500 terms offering definitions of styles, the components of buildings, materials, the various parts of orders and architectural details.

This book arises from a workshop organized by the American Association of Pharmaceutical Scientists entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery," which took place in Parsippany, NJ in September 2004. The workshop focused on the optimization of the drug-like properties of leads in drug discovery. The volume outlines strategies and methodologies designed to guide pharmaceutical and biotechnology companies through the drug discovery and development process.

In Making Dystopia, distinguished architectural historian James Stevens Curl tells the story of the advent of architectural Modernism in the aftermath of the First World War, its protagonists, and its astonishing, almost global acceptance after 1945. He argues forcefully that the triumph of architectural Modernism in the second half of the twentieth century led to massive destruction, the creation of alien urban landscapes, and a huge waste of resources. Moreover, the coming of Modernism was not an inevitable, seamless evolution, as many have insisted, but a massive, unparalled disruption that demanded a clean slate and the elimination of all ornament, decoration, and choice. Tracing the effects of the Modernist revolution in architecture to the present, Stevens Curl argues that, with each passing year, so-called 'iconic' architecture by supposed 'star' architects has become more and more bizarre, unsettling, and expensive, ignoring established contexts and proving to be stratospherically remote from the aspirations and needs of humanity. In the elite world of contemporary architecture, form increasingly follows finance, and in a society in which the 'haves' have more and more, and the 'have-nots' are ever more marginalized, he warns that contemporary architecture continues to stack up huge potential problems for the future, as housing costs spiral out of control, resources are squandered on architectural bling, and society fractures. This courageous, passionate, deeply researched, and profoundly argued book should be read by everyone concerned with what is around us. Its combative critique of the entire Modernist architectural project and its apologists will be highly controversial to many. But it contains salutary warnings that we ignore at our peril. And it asks awkward questions to which answers are long overdue.

Containing over 6,000 entries from Aalto to Zwinger and written in a clear and concise style, this authoritative dictionary covers architectural history in detail, from ancient times to the present day. It also includes concise biographies of hundreds of architects from history (excluding living persons), from Sir Francis Bacon and Imhotep to Liang Ssu-ch'eng and Francis Inigo Thomas. The text is complemented by over 260 beautiful and meticulous line drawings, labelled cross-sections, and diagrams. These include precise drawings of typical building features, making it easy for readers to identify particular period styles. This third edition of The Oxford Dictionary of Architecture has been extensively revised and expanded, with over 900 new entries including hundreds of definitions of garden and landscape terms such as Baroque garden, floral clock, hortus conclusus, and Zen garden-design. Each entry is followed by a mini-bibliography, with suggestions for further reading. The full bibliography to the first edition (previously only available online) has also been fully updated and expanded, and incorporated into this new edition. This is an essential work of reference for anyone with an interest in architectural and garden history. With clear descriptions providing in-depth analysis, it is invaluable for students, professional architects, art historians, and anyone interested in architecture and garden design, and provides a fascinating wealth of information for the general reader.