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Antibodies are crucial to the fine specificity of the immune
system. An effective functioning of these molecules requires
interaction with immune cells. Receptors for antibodies, Fc
receptors, provide this critical link between the humoral and
cellular branches of the immune system. This book presents a
comprehensive overview of the different Fc receptors currently
recognized. The first part of the book contains state-of-the-art
overviews on the biological role of FcR. The latest information on
FcR heterogeneity, FcR physiology, FcR-ligand recognition, their
crucial coordinating role in immunity, interactions with other
immunoreceptors, and the role of FcR in immunoglobulin transport
and catabolism are discussed. The clinical importance of FcR is
developed in the second part of the book. The well-recognized roles
of FcR in allergy, inflammation, infectious diseases, autoimmune
disorders, and immunotherapeutic importance are reviewed. The
information in this book is easily accessible and should be helpful
for researchers and clinical specialists as a convenient overview
of the field, as well as a comprehensive introduction for students
starting in this area of research.
Antibodies are crucial to the fine specificity of the immune
system. An effective functioning of these molecules requires
interaction with immune cells. Receptors for antibodies, Fc
receptors, provide this critical link between the humoral and
cellular branches of the immune system. This book presents a
comprehensive overview of the different Fc receptors currently
recognized. The first part of the book contains state-of-the-art
overviews on the biological role of FcR. The latest information on
FcR heterogeneity, FcR physiology, FcR-ligand recognition, their
crucial coordinating role in immunity, interactions with other
immunoreceptors, and the role of FcR in immunoglobulin transport
and catabolism are discussed. The clinical importance of FcR is
developed in the second part of the book. The well-recognized roles
of FcR in allergy, inflammation, infectious diseases, autoimmune
disorders, and immunotherapeutic importance are reviewed. The
information in this book is easily accessible and should be helpful
for researchers and clinical specialists as a convenient overview
of the field, as well as a comprehensive introduction for students
starting in this area of research.
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