to Nitric Oxide Biology.- 1. Nitric Oxide Synthesis and Actions.- 2. Reactive Oxygen and Reactive Nitrogen Species in the Lung.- Role of Endogenous Nitric Oxide in the Lung.- 3. Non-Adrenergic Non-Cholinergic Neurotransmission in the Airways: Role of Nitric Oxide.- 4. Localisation of Nitric Oxide Synthases in the Lung.- 5. Role of Nitric Oxide in the Regulation of Pulmonary Vascular Tone.- 6. Nitric Oxide and Bronchial Hyperresponsiveness.- 7. Bronchodilator Actions of Nitric Oxide and Related Compounds.- 8. Role of Nitric Oxide in Airway Inflammation.- Therapeutic Potential of Inhalded Nitric Oxide and Nitric Oxide Synthase Inhibitors in Lung Disease.- 9. Nitric Oxide in Exhaled Air: Relevance in Inflammatory Lung Disease.- 10. Luminal Nitric Oxide in the Upper Airways: Implications for Local and Distal Sites of Action.- 11. Inhaled Nitric Oxide as a Therapy for Diseases of the Pulmonary Vasculature.- 12. Combinded Use of Nitric Oxide and Nitric Oxide Synthase Inhibitors as a Possible Therapeutic Approach.

Azari's life has been split in two and the halves are as different as lemons and mangoes. Running links the two parts of her life: sometimes when she runs it is because she wants to, because she feels strong and free. But sometimes it is because she has no other choice. When Azari and her mother flee for their lives to Ireland they are put in a Direct Provision Centre. They must share a room with a stranger, eat food they don't know the name of and answer intrusive questions from authorities. Azari's life has secrets; she must tell them so she can stop running and live a life where she can make her own decisions.

The name "Historical Society" or "Historic House" has a bad rap. Before potential visitors even know your museum, they may assume it's not for them, even if you lead progressive, inclusive tours and host innovative programs. If you're part of the leadership team of a historic house museum or historical society, you may have considered rebranding -- either renaming your organization or developing a new look - to be more appealing to a younger, more diverse audience or to reflect changes to your mission, interpretation, site, etc. Using examples from museums of all sizes across the country, this book helps you decide whether to move forward with a rebranding effort and give you a concrete outline to work from. The book will help you: -Decide if you should rebrand (and that you're not just putting lipstick on a pig) -Nitty-gritty details about how to go about it -How to react when someone says you're making a huge mistake -How much it will cost and where you can cut corners -How to evaluate what you've done. Rebranding: A Guide for Historic Houses, Museums, Sites and Organizations is a step-by-step guide that helps Executive Directors, Board members, and staff at history organizations decide if it's time to rebrand and, if so, how to go about it. The book will guide readers through the process of deciding if a rebranding is in order, testing ideas, developing a plan and budget, implementing the launch, and even handling naysayers. It's an essential guide for anyone rebranding a history organization.

The name "Historical Society" or "Historic House" has a bad rap. Before potential visitors even know your museum, they may assume it's not for them, even if you lead progressive, inclusive tours and host innovative programs. If you're part of the leadership team of a historic house museum or historical society, you may have considered rebranding -- either renaming your organization or developing a new look - to be more appealing to a younger, more diverse audience or to reflect changes to your mission, interpretation, site, etc. Using examples from museums of all sizes across the country, this book helps you decide whether to move forward with a rebranding effort and give you a concrete outline to work from. The book will help you: -Decide if you should rebrand (and that you're not just putting lipstick on a pig) -Nitty-gritty details about how to go about it -How to react when someone says you're making a huge mistake -How much it will cost and where you can cut corners -How to evaluate what you've done. Rebranding: A Guide for Historic Houses, Museums, Sites and Organizations is a step-by-step guide that helps Executive Directors, Board members, and staff at history organizations decide if it's time to rebrand and, if so, how to go about it. The book will guide readers through the process of deciding if a rebranding is in order, testing ideas, developing a plan and budget, implementing the launch, and even handling naysayers. It's an essential guide for anyone rebranding a history organization.

Facilitating Practitioner Research: Developing transformational partnerships addresses the complex dilemmas and issues that arise in practitioner inquiry. It recognises that facilitating practitioner research is far more than providing advice about method adoption, important as that contribution is; or even modelling research practices and drawing attention to appropriate resources and theories. It also requires the evolution of strong reciprocal partnerships that will contribute to professional knowledge formation in both the academy and the field.

When such engagement is undertaken then matters associated with authentic praxis development for field based and academic practitioners emerge. The authors explore:

• how praxis, as practice that can always be judged in terms of what is and what ought to be, can be analysed in terms of functional and substantive rationality as well as life, world and system issues.
• how a transformative partnership requires particular professional attitudes of practitioners and academic
• the underlying potential of practitioner inquiry where agency is afforded as a democratic principle to all who participate, including the consequential stakeholders; the students in our schools and universities.

It draws upon extensive case studies from The Netherlands, Sweden and Australia which not only illustrate and illuminate, but also highlight contradictions and tensions. The case studies exhibit issues related to the quality of the partnerships between the academy and the field and the ways in which quality impacts upon practice. Additionally, the varying social geographies allow a discussion of different intellectual traditions, belief systems, problem settings, questions, and discourses.

Facilitating Practitioner Research: Developing transformational partnerships will appeal internationally to academics involved with practitioner research. It will also prove useful to practitioners across the education sectors, including researchers, teachers and those involved in education policy.

Facilitating Practitioner Research: Developing transformational partnerships addresses the complex dilemmas and issues that arise in practitioner inquiry. It recognises that facilitating practitioner research is far more than providing advice about method adoption, important as that contribution is; or even modelling research practices and drawing attention to appropriate resources and theories. It also requires the evolution of strong reciprocal partnerships that will contribute to professional knowledge formation in both the academy and the field. When such engagement is undertaken then matters associated with authentic 'praxis development' for field based and academic practitioners emerge. The authors explore: how praxis, as practice that can always be judged in terms of 'what is' and 'what ought to be', can be analysed in terms of functional and substantive rationality as well as life, world and system issues. how a transformative partnership requires particular professional attitudes of practitioners and academic the underlying potential of practitioner inquiry where agency is afforded as a democratic principle to all who participate, including the consequential stakeholders; the students in our schools and universities. It draws upon extensive case studies from The Netherlands, Sweden and Australia which not only illustrate and illuminate, but also highlight contradictions and tensions. The case studies exhibit issues related to the quality of the partnerships between the academy and the field and the ways in which quality impacts upon practice. Additionally, the varying social geographies allow a discussion of different intellectual traditions, belief systems, problem settings, questions, and discourses. Facilitating Practitioner Research: Developing transformational partnerships will appeal internationally to academics involved with practitioner research. It will also prove useful to practitioners across the education sectors, including researchers, teachers and those involved in education policy.

Designed as a professional complement to Sarah Naish's bestselling A-Z of Therapeutic Parenting, this tried and tested resource offers practical tools for all professionals supporting therapeutic families. Based on the latest research, and with photocopiable worksheets, pro formas and charts to use with parents, these tools will help you to build supportive and stable relationships with families and reduce family breakdown. The resource is structured into three parts: 1. The Trauma Tracker Tool - designed to support the stability of the family and to predict possible incidents by providing an understanding of the presenting behaviours in the context of the child's history 2. The Developmental Foundation Planner - to help professionals to identify and address unmet developmental needs in a structured way as soon as a child is placed with a family and thereby help reduce instances of family breakdown 3. The Behaviour - Assessment of Impact and Resolution Tool (BAIRT) - which enables practitioners of most levels to engage in a step by step intervention, breaking down the most complex behaviours with a problem solving supportive process, thereby reducing the effects of blocked care and enabling engagement with parents in an honest, positive process. Simple to use, and easy to implement, these tools will enable you to create therapeutic, trauma-informed assessments, intervention and support.

Whether you're sharing data between two internal systems or building an API so that users can access their data, this practical guide has everything you need to build APIs with PHP. Author Lorna Jane Mitchell provides lots of hands-on code samples, real-world examples, and advice based on her extensive experience to guide you through the process-from the underlying theory to methods for making your service robust.You'll learn how to use this language to work with JSON, XML, and other web service technologies. This updated second edition includes new tools and features that reflect PHP updates and changes on the Web.Explore HTTP, from the request/response cycle to its verbs, headers, and cookiesWork with and publish webhooks-user-defined HTTP callbacksDetermine whether JSON or XML is the best data format for your applicationGet advice for working with RPC, SOAP, and RESTful servicesUse several tools and techniques for debugging HTTP web servicesChoose the service that works best for your application, and learn how to make it robustDocument your API-and learn how to design it to handle errors

This is the go-to guide for practitioners, parents and carers who want to expand their understanding and skills for therapeutic parenting - a deeply nurturing parenting style particularly effective for children who have experienced trauma or adversity. It provides an easy to understand explanation of the latest theory and research in trauma and neuroscience, and explains how these relate to everyday parenting strategies. It provides clarity on complex areas, such as early developmental trauma in children, and insights into key challenges, including managing transitions, sibling relationships, challenging behaviour, the teenage years, and how to find time and space for self-care. With experience, professional expertise, and text features to aid learning throughout, this book is the one-stop shop for everyone wanting to truly understand every aspect of therapeutic parenting and trauma.

All families of children affected by trauma are on a journey, and this book will help to guide you and your family on your journey from trauma to trust. Sarah Naish shares her own experiences of adopting five siblings. She describes how to use therapeutic parenting - a deeply nurturing parenting style - to overcome common challenges when raising children who have experienced trauma. The book describes a series of difficult episodes for her family, exploring both parent's and child's experiences of the same events - with the child's experience written by a former fostered child - and in doing so reveals the very good reasons why traumatized children behave as they do. The book explores the misunderstandings that grow between parents and their children, and provides comfort to the reader - you are not the only family going through this! Full of insights from a family and others who have really been there, this book gives you advice and strategies to help you and your family thrive.

The moving story of a Kashmiri boy soldier, from a prize-winning Irish author. It's an ordinary morning at nine-year-old Rafiq's school in rural Kashmir when the silence of dawn prayers is ripped apart by gunfire. Soldiers of the Kashmir Freedom Fighters have raided the village in search of new recruits - they scrawl a line in chalk across the schoolroom wall, and any boy whose height reaches the line will be taken to fight. Rafiq is tall for his age - the first boy to cross the chalkline into a life of brutality and terrorism. This is the story of Rafiq's transformation from child to boy soldier, as he is indoctrinated into the cause of fanatical belief. But his family have not forgotten him; when he can no longer recognize himself, they remember the boy he was, and reach out a hand of redemption as he spirals towards a final act of atrocity.

Discover how to apply the principles of OOP, types, and package management the right way Key Features Explore the latest PHP 8.1 features and modern web development practices Refactor your legacy codebase using modern features and styles in PHP Create your own Composer packages that can be reused across all PHP projects Book DescriptionPHP has come a long way since its introduction. While the language has evolved with PHP 8, there are still a lot of websites running on a version of PHP that is no longer supported. If you are a PHP developer working with legacy PHP systems and want to discover the tenants of modern PHP, this is the book for you. The Art of Modern PHP 8 walks you through the latest PHP features and language concepts. The book helps you upgrade your knowledge of PHP programming and practices. Starting with object-oriented programming (OOP) in PHP and related language features, you'll work through modern programming techniques such as inheritance, understand how it contrasts with composition, and finally look at more advanced language features. You'll learn about the MVC pattern by developing your own MVC system and advance to understanding what a DI container does by building a toy DI container. The book gives you an overview of Composer and how to use it to create reusable PHP packages. You'll also find techniques for deploying these packages to package libraries for other developers to explore. By the end of this PHP book, you'll have equipped yourself with modern server-side programming techniques using the latest versions of PHP. What you will learn Understand how to use modern PHP features such as objects, types, and more Get to grips with PHP package management using Composer Explore dependency injection for your PHP applications Find out what the differences are between legacy and modern PHP 8 code and practices Write clean PHP code and implement design patterns Get hands-on with modern PHP using examples applying MVC and DI techniques Who this book is forThe book is for existing PHP developers and CTO-level professionals who are working with PHP technologies, including legacy PHP, in production. The book assumes beginner-level knowledge of PHP programming as well as experience with server-side development.