New technologies in 3D printing offer innovative capabilities in surgery, biomedical engineering and nanotechnology. This hot topic title synthesizes the most up-to-date information on 3D printing and provides guidance on the optimal application in today's surgical practice, from evaluation in the technology, patient education uses, to ethics and intellectual property, through to virtual reality and future opportunities. Includes expert guidance on the challenges, opportunities, and limitations of 3D printing in the field of surgery. Covers patient and surgical education, ethics and intellectual property, quality and safety, 3D printing as it relates to nanotechnology, tissue engineering, virtual augmented reality, and more. Consolidates today's available information in this rapidly growing area into a single convenient resource.

Cardiovascular and Coronary Artery Imaging, Volume Two presents the basics of echocardiography, nuclear imaging and magnetic resonance imaging (MRI) and provides insights into their appropriate use. The book covers state-of-the-art approaches for automated non-invasive systems for early cardiovascular and coronary artery disease diagnosis. It includes several prominent imaging modalities such as MRI, CT and PET technologies. Other sections focus on major trends and challenges in this area and present the latest techniques for cardiovascular and coronary image analysis.

State of the Art in Neural Networks and Their Applications presents the latest advances in artificial neural networks and their applications across a wide range of clinical diagnoses. Advances in the role of machine learning, artificial intelligence, deep learning, cognitive image processing and suitable data analytics useful for clinical diagnosis and research applications are covered, including relevant case studies. The application of Neural Network, Artificial Intelligence, and Machine Learning methods in biomedical image analysis have resulted in the development of computer-aided diagnostic (CAD) systems that aim towards the automatic early detection of several severe diseases. State of the Art in Neural Networks and Their Applications is presented in two volumes. Volume 1 covers the state-of-the-art deep learning approaches for the detection of renal, retinal, breast, skin, and dental abnormalities and more.

Neural Engineering for Autism Spectrum Disorder, Volume One: Imaging and Signal Analysis Techniques presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, infrared spectroscopy, sMRI, fMRI, DTI, social behaviors and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, feature selection, and analysis of blood oxygen level-dependent (BOLD) signals are presented for detection and estimation of the degree of ASD.

Data compiled by the Center for Disease Control and Prevention indicates an alarming and continuing increase in the prevalence of autism. Despite intensive research during the last few decades, autism remains a behavioral defined syndrome wherein diagnostic criteria lack in construct validity. And, contrary to other conditions like diabetes and hypertension, there are no biomarkers for autism. However, new imaging methods are changing the way we think about autism, bringing us closer to a falsifiable definition for the condition, identifying affected individuals earlier in life, and recognizing different subtypes of autism. The imaging modalities discussed in this book emphasize the power of new technology to uncover important clues about the condition with the hope of developing effective interventions. Imaging the Brain in Autism was created to examine autism from a unique perspective that would emphasize results from different imaging technologies. These techniques show brain abnormalities in a significant percentage of patients, abnormalities that translate into aberrant functioning and significant clinical symptomatology. It is our hope that this newfound understanding will make the field work collaborative and provide a path that minimizes technical impediments.

State of the Art in Neural Networks and Their Applications, Volume Two presents the latest advances in artificial neural networks and their applications across a wide range of clinical diagnoses. The book provides over views and case studies of advances in the role of machine learning, artificial intelligence, deep learning, cognitive image processing, and suitable data analytics useful for clinical diagnosis and research applications. The application of neural network, artificial intelligence and machine learning methods in biomedical image analysis have resulted in the development of computer-aided diagnostic (CAD) systems that aim towards the automatic early detection of several severe diseases. State of the Art in Neural Networks and Their Applications is presented in two volumes. Volume One: Neural Networks in Oncology Imaging covers lung cancer, prostate cancer, and bladder cancer. Volume Two: Neural Networks in Brain Disorders and Other Diseases covers autism spectrum disorder, Alzheimer's disease, attention deficit hyperactivity disorder, hypertension, and other diseases. Written by experienced engineers in the field, these two volumes will help engineers, computer scientists, researchers, and clinicians understand the technology and applications of artificial neural networks.

Neural Engineering for Autism Spectrum Disorder, Volume Two: Diagnosis and Clinical Analysis presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, magnetic resonance spectroscopy, MRI, fMRI, DTI, video analysis of sensory-motor and social behaviors, and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, fuzzy model and temporal fractal analysis of rest state BOLD signals and brain signals are also presented. A clinical guide for general practitioners is provided along with a variety of assessment techniques such as magnetic resonance spectroscopy. The book is presented in two volumes, including Volume One: Imaging and Signal Analysis Techniques comprised of two Parts: Autism and Medical Imaging, and Autism and Signal Analysis. Volume Two: Diagnosis and Treatment includes Autism and Clinical Analysis: Diagnosis, and Autism and Clinical Analysis: Treatment.

Atherosclerosis is a degenerative process affecting blood vessels, which determines narrowing of the lumen, plaque growth, and hardening of the walls. It is a risk factor for cardiovascular diseases. The focus of this book is on the management of the atherosclerotic disease. The coverage of this book spans from histological presentation of the various stages of atherosclerotic lesions to the earliest studies in atherosclerosis therapy, from advanced clinical diagnosis to monitoring, follow-up, and home-care of the atherosclerotic patient. The book shows well-established diagnostic techniques covering several medical imaging modalities such as Ultrasounds, IVUS, MRI, Computer Tomography, along with new trends in early and advanced atherosclerosis diagnosis (innovative drugs and tissue characterization procedures). Surgical standards will be presented along with innovative experimental trials for the treatment of the atherosclerotic patient. The book will also cover emerging techniques based on molecular imaging and vibro-acoustics.

Cardiovascular and Coronary Artery Imaging, Volume One covers state-of-the-art approaches for automated non-invasive systems in early cardiovascular disease diagnosis. The book includes several prominent imaging modalities, such as MRI, CT and PET technologies. A special emphasis is placed on automated imaging analysis techniques, which are important to biomedical imaging analysis of the cardiovascular system. This is a comprehensive, multi-contributed reference work that details the latest developments in spatial, temporal and functional cardiac imaging.

Provides a comprehensive overview of machine learning and deep learning techniques for biomedical imaging Includes thoracic imaging, abdominal imaging, brain imaging, and retinal imaging Covers new and emerging methods in machine learning Features contributions from leading experts Presents tools to improve computer aided diagnosis

Cognitive Informatics, Computer Modelling, and Cognitive Science: Theory, Case Studies, and Applications presents the theoretical background and history of cognitive science to help readers understand its foundations, philosophical and psychological aspects, and applications in a wide range of engineering and computer science case studies. Cognitive science, a cognitive model of the brain, knowledge representation, and information processing in the human brain are discussed, as is the theory of consciousness, neuroscience, intelligence, decision-making, mind and behavior analysis, and the various ways cognitive computing is used for information manipulation, processing and decision-making. Mathematical and computational models, structures and processes of the human brain are also covered, along with advances in machine learning, artificial intelligence, cognitive knowledge base, deep learning, cognitive image processing and suitable data analytics.

Cognitive Informatics, Computer Modelling, and Cognitive Science: Volume Two, Application to Neural Engineering, Robotics, and STEM presents the practical, real-world applications of Cognitive Science to help readers understand how it can help them in their research, engineering and academic pursuits. The book is presented in two volumes, covering Introduction and Theoretical Background, Philosophical and Psychological Theory, and Cognitive Informatics and Computing. Volume Two includes Statistics for Cognitive Science, Cognitive Applications and STEM Case Studies. Other sections cover Cognitive Informatics, Computer Modeling and Cognitive Science: Application to Neural Engineering, Robotics, and STEM. The book's authors discuss the current status of research in the field of Cognitive Science, including cognitive language processing that paves the ways for developing numerous tools for helping physically challenged persons, and more.

Diabetes and Fundus OCT brings together a stellar cast of authors who review the computer-aided diagnostic (CAD) systems developed to diagnose non-proliferative diabetic retinopathy in an automated fashion using Fundus and OCTA images. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to help reduce the amount of time spent on source-searching and instead focus on actual research and the clinical application. This reference depicts the current clinical understanding of diabetic retinopathy, along with the many scientific advances in understanding this condition. As the role of optical coherence tomography (OCT) in the assessment and management of diabetic retinopathy has become significant in understanding the vireo retinal relationships and the internal architecture of the retina, this information is more critical than ever.

Today's healthcare organizations must focus on a lot more than just the health of their clients. The infrastructure it takes to support clinical-care delivery continues to expand, with information technology being one of the most significant contributors to that growth. As companies have become more dependent on technology for their clinical, administrative, and financial functions, their IT departments and expenditures have had to scale quickly to keep up. However, as technology demands have increased, so have the options for reliable infrastructure for IT applications and data storage. The one that has taken center stage over the past few years is cloud computing. Healthcare researchers are moving their efforts to the cloud because they need adequate resources to process, store, exchange, and use large quantities of medical data. Cloud Computing in Medical Imaging covers the state-of-the-art techniques for cloud computing in medical imaging, healthcare technologies, and services. The book focuses on Machine-learning algorithms for health data security Fog computing in IoT-based health care Medical imaging and healthcare applications using fog IoT networks Diagnostic imaging and associated services Image steganography for medical informatics This book aims to help advance scientific research within the broad field of cloud computing in medical imaging, healthcare technologies, and services. It focuses on major trends and challenges in this area and presents work aimed to identify new techniques and their use in biomedical analysis.

Stochastic Modeling for Medical Image Analysis provides a brief introduction to medical imaging, stochastic modeling, and model-guided image analysis. Today, image-guided computer-assisted diagnostics (CAD) faces two basic challenging problems. The first is the computationally feasible and accurate modeling of images from different modalities to obtain clinically useful information. The second is the accurate and fast inferring of meaningful and clinically valid CAD decisions and/or predictions on the basis of model-guided image analysis. To help address this, this book details original stochastic appearance and shape models with computationally feasible and efficient learning techniques for improving the performance of object detection, segmentation, alignment, and analysis in a number of important CAD applications. The book demonstrates accurate descriptions of visual appearances and shapes of the goal objects and their background to help solve a number of important and challenging CAD problems. The models focus on the first-order marginals of pixel/voxel-wise signals and second- or higher-order Markov-Gibbs random fields of these signals and/or labels of regions supporting the goal objects in the lattice. This valuable resource presents the latest state of the art in stochastic modeling for medical image analysis while incorporating fully tested experimental results throughout.

There is an urgent need to develop and integrate new statistical, mathematical, visualization, and computational models with the ability to analyze Big Data in order to retrieve useful information to aid clinicians in accurately diagnosing and treating patients. The main focus of this book is to review and summarize state-of-the-art big data and deep learning approaches to analyze and integrate multiple data types for the creation of a decision matrix to aid clinicians in the early diagnosis and identification of high risk patients for human diseases and disorders. Leading researchers will contribute original research book chapters analyzing efforts to solve these important problems.

Provides a comprehensive overview of machine learning and deep learning techniques for biomedical imaging Includes thoracic imaging, abdominal imaging, brain imaging, and retinal imaging Covers new and emerging methods in machine learning Features contributions from leading experts Presents tools to improve computer aided diagnosis

This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.

As one of the most important tasks in biomedical imaging, image segmentation provides the foundation for quantitative reasoning and diagnostic techniques. A large variety of different imaging techniques, each with its own physical principle and characteristics (e.g., noise modeling), often requires modality-specific algorithmic treatment. In recent years, substantial progress has been made to biomedical image segmentation. Biomedical image segmentation is characterized by several specific factors. This book presents an overview of the advanced segmentation algorithms and their applications.

Digital fundus images can effectively diagnose glaucoma and diabetes retinopathy, while infrared imaging can show changes in the vascular tissues. Likening the eye to the conventional camera, Image Analysis and Modeling in Ophthalmology explores the application of advanced image processing in ocular imaging. This book considers how images can be used to effectively diagnose ophthalmologic problems. It introduces multi-modality image processing algorithms as a means for analyzing subtle changes in the eye. It details eye imaging, textural imaging, and modeling, and highlights specific imaging and modeling techniques. The book covers the detection of diabetes retinopathy, glaucoma, anterior segment eye abnormalities, instruments on detection of glaucoma, and development of human eye models using computational fluid dynamics and heat transfer principles to predict inner temperatures of the eye from its surface temperature. It presents an ultrasound biomicroscopy (UBM) system for anterior chamber angle imaging and proposes an automated anterior segment eye disease classification system that can be used for early disease diagnosis and treatment management. It focuses on the segmentation of the blood vessels in high-resolution retinal images and describes the integration of the image processing methodologies in a web-based framework aimed at retinal analysis. The authors introduce the A-Levelset algorithm, explore the ARGALI system to calculate the cup-to-disc ratio (CDR), and describe the Singapore Eye Vessel Assessment (SIVA) system, a holistic tool which brings together various technologies from image processing and artificial intelligence to construct vascular models from retinal images. The text furnishes the working principles of mechanical and optical instruments for the diagnosis and healthcare administration of glaucoma, reviews state-of-the-art CDR calculation detail, and discusses the existing methods and databases. Image Analysis and Modeling in Ophthalmology includes the latest research development in the field of eye modeling and the multi-modality image processing techniques in ocular imaging. It addresses the differences, performance measures, advantages and disadvantages of various approaches, and provides extensive reviews on related fields.

This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.

Digital fundus images can effectively diagnose glaucoma and diabetes retinopathy, while infrared imaging can show changes in the vascular tissues. Likening the eye to the conventional camera, Image Analysis and Modeling in Ophthalmology explores the application of advanced image processing in ocular imaging. This book considers how images can be used to effectively diagnose ophthalmologic problems. It introduces multi-modality image processing algorithms as a means for analyzing subtle changes in the eye. It details eye imaging, textural imaging, and modeling, and highlights specific imaging and modeling techniques. The book covers the detection of diabetes retinopathy, glaucoma, anterior segment eye abnormalities, instruments on detection of glaucoma, and development of human eye models using computational fluid dynamics and heat transfer principles to predict inner temperatures of the eye from its surface temperature. It presents an ultrasound biomicroscopy (UBM) system for anterior chamber angle imaging and proposes an automated anterior segment eye disease classification system that can be used for early disease diagnosis and treatment management. It focuses on the segmentation of the blood vessels in high-resolution retinal images and describes the integration of the image processing methodologies in a web-based framework aimed at retinal analysis. The authors introduce the A-Levelset algorithm, explore the ARGALI system to calculate the cup-to-disc ratio (CDR), and describe the Singapore Eye Vessel Assessment (SIVA) system, a holistic tool which brings together various technologies from image processing and artificial intelligence to construct vascular models from retinal images. The text furnishes the working principles of mechanical and optical instruments for the diagnosis and healthcare administration of glaucoma, reviews state-of-the-art CDR calculation detail, and discusses the existing methods and databases. Image Analysis and Modeling in Ophthalmology includes the latest research development in the field of eye modeling and the multi-modality image processing techniques in ocular imaging. It addresses the differences, performance measures, advantages and disadvantages of various approaches, and provides extensive reviews on related fields.

Diagnostic and Therapeutic Ultrasound has recently taken an explosive growth for better safer, economic, mobile and high quality healthcare. This technology is very appealing for medical applications because it is non-ionizing, non-invasive and it is available in most of the medical and clinical facilities. Its low cost, when compared with other medical image modalities, makes it one of the preferred tools for medical monitoring, follow-up and diagnosis. Besides the traditional fields of Cardiology and Obstetrics, where it is extensively used for long time, it has became also very useful in the diagnosis of diseases of the prostate, liver and coronaries and carotids atherosclerosis. However, Ultrasound images present poor quality, very low signal to noise ratio and a lot of artifacts. The extraction of useful information from Ultrasound data for diagnosis is a challenge task that makes this medical image modality a very active field of research. The difficulties are being overcome and novel and advanced methods are being proposed for detection, characterization and segmentation of abnormalities in several organs. In fact, Ultrasound application range is vast, covering almost all organs of the human body, including the brain where Tran-cranial Doppler Ultrasound is very important to assess the brain vasculature. This book presents some of the recent advances in Ultrasound imaging technology covering several organs and techniques in a Biomedical Engineering (BME) perspective. The focus of the book is in the algorithms, methodologies and systems developed by multidisciplinary research teams of engineers and physicians for Computer-Aided Diagnosis (CAD) purposes. Cardiovascular and Cancer, the most common life-threatening diseases in western countries, are two of the most important topics focused in the book. However, other advanced issues are also presented such as Intravascular Ultrasound, 3D US and Ultrasound in Computer-Aided Surgery (CAS). Some chapters are direct contributions from medical research groups where Ultrasound has also received great attention in the last decade. By this, new techniques based on Ultrasound were introduced in the clinical practice for diagnosis and therapeutics, mainly in hospital facilities.

This book focuses on image based security techniques, namely visual cryptography, watermarking, and steganography. This book is divided into four sections. The first section explores basic to advanced concepts of visual cryptography. The second section of the book covers digital image watermarking including watermarking algorithms, frameworks for modeling watermarking systems, and the evaluation of watermarking techniques. The next section analyzes steganography and steganalysis, including the notion, terminology and building blocks of steganographic communication. The final section of the book describes the concept of hybrid approaches which includes all image-based security techniques. One can also explore various advanced research domains related to the multimedia security field in the final section. The book includes many examples and applications, as well as implementation using MATLAB, wherever required. Features: Provides a comprehensive introduction to visual cryptography, digital watermarking and steganography in one book Includes real-life examples and applications throughout Covers theoretical and practical concepts related to security of other multimedia objects using image based security techniques Presents the implementation of all important concepts in MATLAB

This book covers state-of-the-art medical image analysis approaches currently pursued in autism research. Chapters cover recent advances in diagnosis using structural neuroimaging. All aspects of imaging are included, such as electrophysiology (EEG, ERP, QEEG, and MEG), postmortem techniques, and advantages and difficulties of depositing/acquiring images in larger databases. The book incorporates 2D, 3D, and 4D imaging and advances scientific research within the broad field of autism imaging.