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Although antidepressants have helped millions worldwide, a
substantial proportion of patients fail to respond or remit. There
is little published information available to clinicians for
diagnosis and management of treatment-resistant depression, causing
them to make difficult decisions regarding treatment options with
very limited data. The editors and their internationally
distinguished team of contributors have set out to address this
problem, giving a critical assessment of all aspects of
treatment-resistant depression: causes, epidemiology, comorbidity,
evaluation, and treatment. This timely book will be invaluable to
clinicians, neuroscientists, researchers, and graduate students.
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