Dr. Lefkowitch is one the most well known experts on liver pathology and has updated the topic since it last published over 5 years ago. Important topics updated include benign liver tumor, vascular disorders of the liver, autoimmune hepatitis, and non-alcoholic fatty liver disease. Special emphasis is given to articles devoted to immunochemistry in liver tumors, hepatic granulomas, and diagnostic pitfalls in liver transplantation.

Dr. Lefkowitch has created a primer on liver pathology for the gastroenterologist that provides depth of clinical coverage in an area not typically covered in depth for gastroenterologists. This issue will provide state-of-the-art reviews in the areas of NAFLD, liver biopsy, liver pathology, hepatitis, and genomics. Articles are specifically devoted to IgG4-related disease and the liver; current concepts in pediatric NAFLD; evaluation of the pediatric liver biopsy; hepatocellular adenomas: morphology and genomics; drug-induced liver injury: the hepatic pathologist's approach; liver pathology in alpha-1-antitrypsin deficiency; immunohistochemistry in the diagnosis of hepatocellular carcinoma; HIV infection, antiretroviral therapy and liver pathology; autoimmune hepatitis overlap syndromes and liver pathology; current perspectives on the pathology of hepatocellular carcinoma and its variants; hepatitis E virus and the liver: clinical settings and liver pathology; hepatic progenitor cells; and cholangiocarcinoma: current genomics and pathology, to name a few.

Trusted for more than 50 years by pathologists in practice and in training, Scheuer's Liver Biopsy Interpretation is a well-organized, superbly illustrated guide designed to help solve diagnostic problems at the microscope. Authored by renowned expert Dr. Jay Lefkowitch and reflecting the extensive experience of the late Dr. Peter Scheuer, this practical text contains technical tips, diagnostic clues, and pearls on all aspects of liver pathology diagnosis, including acute and chronic hepatitis, biliary tract diseases, childhood disorders, and hepatic neoplasms - as well as ancillary topics such as biopsy assessment, laboratory techniques, normal liver histology, and transplantation. Throughout the text, histopathologic features are correlated with clinical features, molecular genetics, and immunohistochemistry to provide a practical account of how pathology impacts the diagnosis and management of liver disease. Covers key topics such as genomic alterations in liver tumours, diagnosis of acute liver allograft rejection, scoring systems for non-alcoholic fatty liver disease, and discussions of immunohistochemical features wherever relevant. Presents the latest information on next generation sequencing and drug-induced liver injury, including adverse reactions to new biologics and alternative medicines to help both the clinician and pathologist avoid diagnostic errors. Features many new illustrations, including over 300 large, full-color and fully annotated photomicrographs that illustrate a wide range of pathologic appearances and help identify each diagnostic entity under discussion. Offers coverage of cytopathology in the assessment of liver tumors to provide further clinical clues to diagnosis. Provides basic overview of major histopathologic diagnostic problems in paediatric liver biopsy, including biliary atresia and several types of progressive familial intrahepatic cholestasis Provides new and updated algorithms, tables and images highlighting key features of each diagnostic entity - ideal as a concise review during sign out or for studying and board preparation. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.