Generations of scholars have studied the multifaceted experiences of the Franciscans in Mexico and how the Franciscan order shaped New Spain and the early Mexican republic. Recent scholarship has given long-overdue attention to the evangelized natives. Most of these works focus on a specific region or period, or on a particular aspect of Franciscan ministries in New Spain. A comprehensive account of the Franciscans in Mexico over the long term has been missing, until now. This book analyzes the Franciscans' engagement with native peoples, creole populations, the viceregal authorities, and the Spanish empire as a whole in order to offer a broad picture of Catholic evangelization in North America while keeping the Franciscans at the center of the story. Published in 2021, during commemoration of the quincentenary of the Spanish-and thus the Franciscan-presence in Mexico, the book brings together the research of junior and senior scholars from Mexico, Spain, and the United States on the long-enduring and far-reaching Franciscan presence in Mexico.