This volume provides a summary description of over three hundred western medieval manuscripts (excluding Greek) acquired by Cambridge University Library since the publication of the mid-nineteenth century printed catalogue; for the most part, no published descriptions have hitherto existed. Concentrating on contents and provenance, the catalogue covers manuscripts from a sixth-century fragment of Augustine to a translation by Erasmus of a work by Plutarch, and in Latin, English, French, Italian, Spanish, and Welsh. The descriptions are complemented with an introductory survey of the collection and its history.