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Periods of environmental hypoxia (Low Oxygen Availability) are
extremely common in aquatic systems due to both natural causes such
as diurnal oscillations in algal respiration, seasonal flooding,
stratification, under ice cover in lakes, and isolation of densely
vegetated water bodies, as well as more recent anthropogenic causes
(e.g. eutrophication). In view of this, it is perhaps not
surprising that among all vertebrates, fish boast the largest
number of hypoxia tolerant species; hypoxia has clearly played an
important role in shaping the evolution of many unique adaptive
strategies. These unique adaptive strategies either allow fish to
maintain function at low oxygen levels, thus extending hypoxia
tolerance limits, or permit them to defend against the metabolic
consequences of oxygen levels that fall below a threshold where
metabolic functions cannot be maintained.
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