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Over the past decade, techniques have been developed and
implemented to observe metabolism noninvasively in localized
regions of intact, living experimental animals and humans through
the use of magnetic resonance spectroscopy (MRS). At the same time,
magnetic resonance imaging (MRI) techniques developed in the 1970s
and refined in this decade have been increasingly applied as a
powerful clinical tool to probe human anatomy. Because of the
unusual metabolic and physiologic characteristics of malignant
tissues, oncology has been one of the primary focuses of the
application of both MRS and MRI. Although considerable progress has
been made in oncologic applications of magnetic resonance (MR),
further research is needed to realize the full potential of MR in
this area. Consequently, the 21st Annual Detroit Cancer Symposium
entitled "Magnetic Resonance in Experimental and Clin ical
Oncology" was organized to provide a forum for researchers in the
field to report the state of the art of MRS and MRI in oncol ogy,
to discuss future goals for MRS and MRI in oncology, and to define
the research needed to meet those goals. The major emphasis of the
symposium was on MRS due to both the recent widespread availability
of clinical MRS instrumentation and the extensive amount of animal
MRS research performed over the past half decade."
Over the past decade, techniques have been developed and
implemented to observe metabolism noninvasively in localized
regions of intact, living experimental animals and humans through
the use of magnetic resonance spectroscopy (MRS). At the same time,
magnetic resonance imaging (MRI) techniques developed in the 1970s
and refined in this decade have been increasingly applied as a
powerful clinical tool to probe human anatomy. Because of the
unusual metabolic and physiologic characteristics of malignant
tissues, oncology has been one of the primary focuses of the
application of both MRS and MRI. Although considerable progress has
been made in oncologic applications of magnetic resonance (MR),
further research is needed to realize the full potential of MR in
this area. Consequently, the 21st Annual Detroit Cancer Symposium
entitled "Magnetic Resonance in Experimental and Clin ical
Oncology" was organized to provide a forum for researchers in the
field to report the state of the art of MRS and MRI in oncol ogy,
to discuss future goals for MRS and MRI in oncology, and to define
the research needed to meet those goals. The major emphasis of the
symposium was on MRS due to both the recent widespread availability
of clinical MRS instrumentation and the extensive amount of animal
MRS research performed over the past half decade.
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