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In this issue of Neurosurgery Clinics, guest editors Drs. David D.
Limbrick and Jeffrey Leonard bring their considerable expertise to
Chiari I Malformation. Top experts in the field cover key topics
such as comorbidities associated with Chiari I malformation;
orthostatic intolerance and Chiari I malformation; clinical
manifestations of Chiari I malformation; imaging in Chiari I
malformation; posterior fossa decompression for Chiari I
malformation; and more. Contains 21 relevant, practice-oriented
topics sociodemographics of Chiari I malformation; Chiari I
malformation and sleep disordered breathing; complex Chiari:
diagnosis, evaluation, and treatment; new insights into
craniovertebral junction instability in Chiari I malformation;
spine deformity associated with Chiari I malformation and
syringomyelia; and more. Provides in-depth clinical reviews on
Chiari I malformation, offering actionable insights for clinical
practice. Presents the latest information on this timely, focused
topic under the leadership of experienced editors in the field.
Authors synthesize and distill the latest research and practice
guidelines to create clinically significant, topic-based reviews.
This issue will cover chiari malformation in both children and
adult populations. In the past, it was estimated that the condition
occurs in about one in every 1,000 births. However, the increased
use of diagnostic imaging has shown that CM may be much more
common. Complicating this estimation is the fact that some children
who are born with the condition may not show symptoms until
adolescence or adulthood, if at all. CMs occur more often in women
than in men and Type II malformations are more prevalent in certain
groups, including people of Celtic descent.
Since the early 1970s, observers have noted that complying with
environmental regulations might be a significant new factor in
determining the locations of industries involved in world trade.
Two related hypotheses have been offered to explain how
environmental regulations are altering international comparative
advantage in industrial production: first, that stringent
regulations push industries out of the United States and other
advanced industrial nations (the 'industrial flight' hypothesis);
second, that less developed countries compete to attract
multinational industries by minimizing their own regulations (the
'pollution haven' hypothesis). This 1988 study examines the
validity of the industrial-flight and pollution-haven hypotheses
within a broad political and economic framework of theories
purporting to explain international trade and investment.
Since the early 1970s, observers have noted that complying with
environmental regulations might be a significant new factor in
determining the locations of industries involved in world trade.
Two related hypotheses have been offered to explain how
environmental regulations are altering international comparative
advantage in industrial production: first, that stringent
regulations push industries out of the United States and other
advanced industrial nations (the 'industrial flight' hypothesis);
second, that less developed countries compete to attract
multinational industries by minimizing their own regulations (the
'pollution haven' hypothesis). This 1988 study examines the
validity of the industrial-flight and pollution-haven hypotheses
within a broad political and economic framework of theories
purporting to explain international trade and investment.
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