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Caspases are proteases that are responsible for the initiation and
execution of cell death pathways in developmental, inflammatory and
pharmacological paradigms. Caspase activity is required for the
execution of apoptotic cell death through the proteolytic cleavage
of approximately one thousand substrates that result in the
apoptotic phenotype. This book provides new research and discusses
the roles and significance caspases have in cell death and disease.
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