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ICP-MS and Trace Element Analysis as Tools for Better Understanding
Medical Conditions, Volume 97 discusses trace elements and how they
play an important role in biological functions and metabolism in
the human body. Chapters cover Biomedical analysis by ICP-MS: A
focus on single cell, Advanced statistical tools and machine
learning applied to trace element analysis associated with medical
conditions, ICP-MS as a tool to understand trace element
homeostasis in neurological disorders, High-precision isotopic
analysis of essential mineral elements - possibilities for medical
diagnosis and prognosis, Exploring ICP-MS as a versatile technique:
From imaging to chemical speciation, and more.
This book presents an exploratory analysis based on proteomic and
ionomics studies comparing the blood serum of patients with bipolar
disorder (BD), healthy controls, patients with schizophrenia (SCZ),
and patients with other disorders (OD) in order to identify
biomarkers of BD. Bipolar disorder is a psychiatric condition that
affects thousands of people worldwide. The absence of biomarkers
for BD has resulted in misdiagnosis and ineffective treatment in
some patients, causing additional health problems and high costs
for health systems. As such, this book evaluates various strategies
for sample preparation for proteomic and ionomic studies in order
to simplify complex serum samples and allow the quantification of
chemical species (proteins and metal ions), which are potential
candidates for BD biomarkers. In addition, it describes the
development of a new membrane-based methodology for extracting
urine proteins to be used in biomarker discovery.
This book presents an exploratory analysis based on proteomic and
ionomics studies comparing the blood serum of patients with bipolar
disorder (BD), healthy controls, patients with schizophrenia (SCZ),
and patients with other disorders (OD) in order to identify
biomarkers of BD. Bipolar disorder is a psychiatric condition that
affects thousands of people worldwide. The absence of biomarkers
for BD has resulted in misdiagnosis and ineffective treatment in
some patients, causing additional health problems and high costs
for health systems. As such, this book evaluates various strategies
for sample preparation for proteomic and ionomic studies in order
to simplify complex serum samples and allow the quantification of
chemical species (proteins and metal ions), which are potential
candidates for BD biomarkers. In addition, it describes the
development of a new membrane-based methodology for extracting
urine proteins to be used in biomarker discovery.
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