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Nicotine and Other Tobacco Compounds in Neurodegenerative and
Psychiatric Diseases: Epidemiological Data on Smoking and
Preclinical and Clinical Data on Nicotine provides a comprehensive
summary of the epidemiological data on smoking and several
neurological disorders, including Alzheimer's disease, Parkinson's
disease, Multiple Sclerosis, Tourette's syndrome, schizophrenia,
anxiety, depression and ADHD, as well as preclinical and clinical
data on the effects of nicotine. Despite the obvious and undisputed
harmful nature of smoking, evidence suggests that some tobacco and
tobacco smoke-derived constituents may offer neuroprotective
effects, possibly in combinations, rather than individually. This
unprecedented book describes the complex relationships between
smoking and neurological disease and the bioactive compounds found
in tobacco. It provides a comprehensive review of nicotine and
other compounds found in tobacco plant, with scientific evidence of
neuroprotective and anti-inflammatory effects that may act in
conjunction with nicotine to exert neuroprotective effects observed
in smokers. By presenting findings beyond harmful cigarette smoke
effects, attention can be drawn to individual compounds of tobacco
that may serve as inspiration for further therapy development.
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