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Recent research suggests that adult growth hormone (GH) deficiency,
whether of pathological or physiological origin, is associated with
a dis tinct syndrome that includes alterations in body composition,
endocrine metabolic function, immune competence, and physical and
psychosocial well-being. Not surprisingly, substantial
investigative effort is currently focused on validating the above
hypothesis and on determining whether restoration of a normal
GH-IGF-I axis in various states of adult GH deficiency is
clinically useful, safe, and cost-beneficial. This book contains
the proceedings from the Symposium on GHRH, GH, and IGF-I: Basic
and Clinical Advances, held December 9 to 12, 1993, in San Diego,
California, and sponsored by Serono Symposia USA, Inc. The
conference was meant to highlight selected novel and exciting
clinical research developments related to possible therapeutic uses
of recombinant human GH and IGF-I, GHRH, GH releasing peptides, and
related GH secretagogues. This meeting occurred only one year after
a similar Serono symposium that was somewhat more oriented to novel
basic science discoveries, thus attesting to the current scientific
and clinical interest in this area.
Recent research suggests that adult growth hormone (GH) deficiency,
whether of pathological or physiological origin, is associated with
a dis tinct syndrome that includes alterations in body composition,
endocrine metabolic function, immune competence, and physical and
psychosocial well-being. Not surprisingly, substantial
investigative effort is currently focused on validating the above
hypothesis and on determining whether restoration of a normal
GH-IGF-I axis in various states of adult GH deficiency is
clinically useful, safe, and cost-beneficial. This book contains
the proceedings from the Symposium on GHRH, GH, and IGF-I: Basic
and Clinical Advances, held December 9 to 12, 1993, in San Diego,
California, and sponsored by Serono Symposia USA, Inc. The
conference was meant to highlight selected novel and exciting
clinical research developments related to possible therapeutic uses
of recombinant human GH and IGF-I, GHRH, GH releasing peptides, and
related GH secretagogues. This meeting occurred only one year after
a similar Serono symposium that was somewhat more oriented to novel
basic science discoveries, thus attesting to the current scientific
and clinical interest in this area."
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