This book offers a selection of the best papers presented at the annual international scientific conference "Digital Transformation in Industry: Trends, Management, Strategies (DTI2021)," held by the Institute of Economics, Ural Branch of the Russian Academy of Sciences, in Ekaterinburg (Russia) on October 29, 2021. The book focuses on the idea of introduction mechanisms for digitization processes and on highlighting successful digital transformation strategies in all sectors of industry. Key topics include the development of a cyber-physical production system for Industry 4.0; digital design technologies for enhancing the competitiveness of products and companies; digital twin-driven product manufacturing and services; and the effects of the industrial digital transformation on society and the environment. With regard to implementing IT and other technological innovations, lessons learned in developed and developing economies, as well as small and large enterprises, are included. Given its scope, the book offers a valuable asset for researchers and managers of industrial organizations alike.