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Antibiotics are powerful drugs that can prevent and treat
infections, but they are becoming less effective as a result of
drug resistance. Resistance develops because the bacteria that
antibiotics target can evolve ways to defend themselves against
these drugs. When antibiotics fail, there is very little else to
prevent an infection from spreading. Unnecessary use of antibiotics
in both humans and animals accelerates the evolution of
drug-resistant bacteria, with potentially catastrophic personal and
global consequences. Our best defenses against infectious disease
could cease to work, surgical procedures would become deadly, and
we might return to a world where even small cuts are
life-threatening. The problem of drug resistance already kills over
one million people across the world every year and has huge
economic costs. Without action, this problem will become
significantly worse. Following from their work on the Review on
Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim
O’Neill outline the major systematic failures that have led to
this growing crisis. They also provide a set of solutions to tackle
these global issues that governments, industry, and public health
specialists can adopt. In addition to personal behavioral
modifications, such as better handwashing regimens, Superbugs
argues for mounting an offense against this threat through
agricultural policy changes, an industrial research stimulus, and
other broad-scale economic and social incentives.
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