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According to the Institute of Medicine (IOM) and U.S. Food and Drug
Administration (FDA), 'developing new scientific approaches to
detecting, understanding, predicting and preventing adverse events'
was a critical path to the future of drug safety. This book brings
together a collection of state-of-the-art chapters, written by
experts in the drug safety field. It provides information on the
present knowledge of drug side effects and their mitigation
strategy during drug discovery, gives guidance for risk assessment
and promotes evidence-based toxicology. Each specific area of
toxicology relevant for drug discovery is discussed in detail,
including theory, experimental approaches and data interpretation
supported by comprehensive up-to-date references. Many chapters
provide fascinating case studies, which are of general interest for
those who have basic science training and are interested in how
chemicals interact with the human body.
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