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Bioactive Microbial Metabolites: Scope and Challenges not only
focuses on the identification, separation and purification of
bioactive metabolites, the book also provides an understanding of
the metabolic pathways for bioactive metabolites production that
play an important role in modern healthcare as frontline treatments
for many diseases. This is a valuable reference for research
students, academicians and scientists in environmental microbiology
and biotechnology, and for industry personnel related to
microbiology/ biotechnology. The science discussed herein plays an
important role in expanding the market of antibiotics, food and
agriculture but also offers eco-friendly, safer and profitable
solutions to respective industries.
Extremophiles belong to members of all three domains of life, i.e.,
bacteria, archaea, and eukarya. However, a high proportion of
extremophiles are archaea and bacteria. These microbes live under
chemical and physical extremes that are usually lethal to cellular
molecules, yet they not only manage to survive but even thrive in
such conditions. Extremophiles have important practical and
industrial uses. They are a valuable source of industrially
important enzymes also known as extremozymes. Recent research has
revealed that extremozymes have unique structural features
essential for biocatalysis under extreme conditions. Extremozymes
have great commercial values and are known for their potential use
in biotechnology, biomining, and bioremediation. Extremozymes and
their Industrial Applications highlights the current and topical
areas of research in this rapidly growing field of extremophiles
and their applications. Expert researchers from around the globe
are trying to uncover the underlying mechanisms responsible for
their specific adaptations under extreme environments. The topics
covered include the ability of acidophiles to maintain a neutral
intracellular pH, the way psychrophiles "loosen up" their proteins
at low temperatures, and other equally ingenious adaptations and
metabolic strategies that extremophiles use to survive and flourish
under extreme conditions. Extremozymes and their Industrial
Applications also covers the established biotechnological uses of
extremophiles and the most recent and novel applications, including
their exploitation for enzyme production. Potential use of
extremophiles and their enzymes in the generation of sustainable
energy, biomass conversion, agro-waste processing, and biocontrol
of phytopathogens is also covered. The book will be very useful for
researchers and students working in the area of industrial
microbiology and biotechnology, and microbial ecologists. It is
also recommended reference text for those interested in the
biochemistry and microbiology of extremophiles, as well as for
those interested in bioprospecting, biomining, biofuels, and
biodegradation.
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