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China has progressed dramatically since 1978 when the country
started its economic reforms and opened up to the world economy. It
took only three decades for China to develop from a closed,
centrally planned economy with little sea-borne trade into the
world's second largest economy with the largest container shipment
volume in the world. The major coastal cities have been gateways
linking China with the world and have experienced rapid
urbanization and port growth. How has such port growth been speeded
up and realized under strong state control and intervention? How
have ports and their cities affected each other? What lessons can
China's port-cities learn from other countries, regions and cities?
What will be the next stage of port-city interplays in China in
this globalizing era? Answering these questions from a geographical
perspective, James Wang looks into four sets of port-city relations
in China: Economic and functional relations between port and city;
port-city spatial relations; external network relations of cities
through ports; and port-city governance. These relations formulate
a conceptual framework which is used to interpret port-city
interplays in individual ports and cities but also in multi-port
regions such as the Pearl River Delta. Based on the author's own
research and investigations into more than 25 port cities in China
over the past 18 years, this book provides vivid stories about
China and challenge existing theories on port development.
China has progressed dramatically since 1978 when the country
started its economic reforms and opened up to the world economy. It
took only three decades for China to develop from a closed,
centrally planned economy with little sea-borne trade into the
world's second largest economy with the largest container shipment
volume in the world. The major coastal cities have been gateways
linking China with the world and have experienced rapid
urbanization and port growth. How has such port growth been speeded
up and realized under strong state control and intervention? How
have ports and their cities affected each other? What lessons can
China's port-cities learn from other countries, regions and cities?
What will be the next stage of port-city interplays in China in
this globalizing era? Answering these questions from a geographical
perspective, James Wang looks into four sets of port-city relations
in China: Economic and functional relations between port and city;
port-city spatial relations; external network relations of cities
through ports; and port-city governance. These relations formulate
a conceptual framework which is used to interpret port-city
interplays in individual ports and cities but also in multi-port
regions such as the Pearl River Delta. Based on the author's own
research and investigations into more than 25 port cities in China
over the past 18 years, this book provides vivid stories about
China and challenge existing theories on port development.
Discover the Latest Statistical Approaches for Modeling
Exposure-Response Relationships Written by an applied statistician
with extensive practical experience in drug development,
Exposure-Response Modeling: Methods and Practical Implementation
explores a wide range of topics in exposure-response modeling, from
traditional pharmacokinetic-pharmacodynamic (PKPD) modeling to
other areas in drug development and beyond. It incorporates
numerous examples and software programs for implementing novel
methods. The book describes using measurement error models to treat
sequential modeling, fitting models with exposure and response
driven by complex dynamics, and survival analysis with dynamic
exposure history. It also covers Bayesian analysis and model-based
Bayesian decision analysis, causal inference to eliminate
confounding biases, and exposure-response modeling with
response-dependent dose/treatment adjustments (dynamic treatment
regimes) for personalized medicine and treatment adaptation. Many
examples illustrate the use of exposure-response modeling in
experimental toxicology, clinical pharmacology, epidemiology, and
drug safety. Some examples demonstrate how to solve practical
problems while others help with understanding concepts and
evaluating the performance of new methods. The provided SAS and R
codes enable readers to test the approaches in their own scenarios.
Although application oriented, this book also gives a systematic
treatment of concepts and methodology. Applied statisticians and
modelers can find details on how to implement new approaches.
Researchers can find topics for or applications of their work. In
addition, students can see how complicated methodology and models
are applied to practical situations.
Discover the Latest Statistical Approaches for Modeling
Exposure-Response Relationships Written by an applied statistician
with extensive practical experience in drug development,
Exposure-Response Modeling: Methods and Practical Implementation
explores a wide range of topics in exposure-response modeling, from
traditional pharmacokinetic-pharmacodynamic (PKPD) modeling to
other areas in drug development and beyond. It incorporates
numerous examples and software programs for implementing novel
methods. The book describes using measurement error models to treat
sequential modeling, fitting models with exposure and response
driven by complex dynamics, and survival analysis with dynamic
exposure history. It also covers Bayesian analysis and model-based
Bayesian decision analysis, causal inference to eliminate
confounding biases, and exposure-response modeling with
response-dependent dose/treatment adjustments (dynamic treatment
regimes) for personalized medicine and treatment adaptation. Many
examples illustrate the use of exposure-response modeling in
experimental toxicology, clinical pharmacology, epidemiology, and
drug safety. Some examples demonstrate how to solve practical
problems while others help with understanding concepts and
evaluating the performance of new methods. The provided SAS and R
codes enable readers to test the approaches in their own scenarios.
Although application oriented, this book also gives a systematic
treatment of concepts and methodology. Applied statisticians and
modelers can find details on how to implement new approaches.
Researchers can find topics for or applications of their work. In
addition, students can see how complicated methodology and models
are applied to practical situations.
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