As the HIV/AIDS epidemic has grown to become the fourth biggest killer in the world and the leading cause of death in sub-Saharan Africa so the pressure on those working in the field to expand the scale of their activities has increased. Non-governmental organizations (NGOs) have been especially influential in the response to HIV in developing countries and the pressure to increase the scope and impact of this work is particularly strong. "Making an Impact in HIV and AIDS" recognizes that scaling up NGO programmes requires more than just additional resources or the straightforward replication or expansion of interventions. The book analyzes when expansion is appropriate, how to make it effective, how to measure the costs, and what the implications for organizations may be. It examines these issues through the experience of NGOs working in different contexts and in all aspects of HIV/AIDS including prevention, care and support, and mitigating the impact of the epidemic. The author draws on case studies from a range of countries in Africa, Asia and Latin America. She integrates the insights from these experiences with existing thinking and proposes a new typology of approaches to scaling up. Key elements of scaling up are discussed, as are issues such as the risks entailed in growth, motivations for scaling up and the special challenges related to scaling up work on HIV and AIDS. This book is aimed at those active in the HIV/AIDS field who are interested in NGO programmes, and those in the wider development field who are concerned about the impact of HIV/AIDS and what NGOs can do about it. It makes an important contribution to thinking about scaling up NGO activities in general and is particularly relevant as the pressures of the epidemic concern not only the organizations directly involved but also those working on all aspects of development.