This text is intended as a guide to OpenVMS performance management and application design. It features a variety of performance-related topics, and guidelines are given, with examples on how to relieve specific problems It features tuning tips on RDBMs (Oracle, Ingres, and Rdb) and making changes to Sysgen parameters, and specific application tuning (All-in-1, Pathworks, X-Windows and TCP/IP). It covers tuning methodologies, contains information on a range of performance-related topics, and provides information on "rules of thumb" on CPU, memory and disk I/O management. It also covers versions 5.0 and 6.0 of VMS.