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Computational and theoretical tools for understanding biological
processes at the molecular level is an exciting and innovative area
of science. Using these methods to study the structure, dynamics
and reactivity of biomacromolecules in solution, computational
chemistry is becoming an essential tool, complementing the more
traditional methods for structure and reactivity determination.
Modelling Molecular Structure and Reactivity in Biological Systems
covers three main areas in computational chemistry; structure
(conformational and electronic), reactivity and design. Initial
sections focus on the link between computational and spectroscopic
methods in the investigation of electronic structure. The use of
Free Energy calculations for the elucidation of reaction mechanisms
in enzymatic systems is also discussed. Subsequent sections focus
on drug design and the use of database methods to determine ADME
(absorption, distribution, metabolism, excretion) properties. This
book provides a complete reference on state of the art
computational chemistry practised on biological systems. It is
ideal for researchers in the field of computational chemistry
interested in its application to biological systems.
Environmental issues can present some daunting operational concerns
for all types of organization, whether in the private, public and
voluntary sectors. Managing them requires environmental
professionals with a working knowledge of the rapidly developing
body of regulatory measures. This new edition of Environmental
Management in Organizations provides all the management tools,
performance measures and communication strategies that
organizations need to manage their environmental responsibilities
effectively. Leading experts on each topic provide focused
explanations and clear practical guidance, as well as setting out
the context and the key environmental and management drivers. This
edition significantly updates the original handbook to take account
of developments in the environmental agenda, including new
dedicated chapters on climate change, energy, transport,
biodiversity and chemicals. This title is published in association
with IEMA.
The love story of Frank Sinatra and Ava Gardner has never been fully explored or explained--until now. Frank & Ava delves deeply into the lives of these two iconic stars and their turbulent lifelong relationship.
It began in Hollywood's golden age when Ava was emerging as a movie star. But she fell in (and out of) love too easily. Mickey Rooney married her because he wanted another conquest. Artie Shaw treated her like a dumb brunette, giving her a reading list on their honeymoon. Neither marriage lasted a year. Then, after being courted by Howard Hughes and numerous others, along came Frank Sinatra.
His passion for Ava destroyed his marriage and brought him close to ruin. Their wild affair broke all the rules of the prudish era as Frank left his wife and children and pursued Ava on an international stage. They became romantic renegades, with the press following them from location to location.
They married, but then came the quarrels, separations, infidelities, and reconciliations. Eventually, there was a divorce, and they thought it was over. It wasn't.
Through all of the tortured years of separation and splintered affairs with others, they maintained a secretive relationship known only to those who recognized that this was the love of a lifetime. Over the years, they attempted to reconcile, romanced and nurtured each other, right to the end. In Frank & Ava, longtime Sinatra specialist John Brady uncovers the beauty of this epic love story.
Scandalous Narratives of Contemporary Ireland Back to the Gaff is a
new book by new author John P Brady, which describes the excessive
and outrageous nature of Irish night life. Meet an array of
eccentric individuals who populate the bars of Dublin, living lives
of decadence and abandon. Their frolics inevitably lead to a trip
'back to the gaff, ' which in Dublin-speak means gravitating
towards someone's place of residence where the depravity continues.
Many of the characters are figures who prop up some of the city
centre bars and inhabit a parallel universe in which they never
have a normal night out. The mundane is their enemy which they
strike out against at every opportunity, escaping into a world of
vice, where sex is casual and drugs are ubiquitous. 'Brady's
writing renews the reconciliation between introspection and
action.' Shazia Hafiz Ramji, Editor Zouch Magazine 'Keen, witty
observations of ordinary people. John P Brady has a funny twist on
life' Sam North - Editor of Hackwriters Magazine '...like a young
Jack Kerouac...' Alice Walsh - Former editor of The Bohemyth
This Is A New Release Of The Original 1815 Edition.
This Is A New Release Of The Original 1815 Edition.
In Two Volumes. Illustrated with Ecclesiastical, Historical and
Classical Anecdotes.
In Two Volumes. Illustrated with Ecclesiastical, Historical and
Classical Anecdotes.
This scarce antiquarian book is a selection from Kessinger
Publishing's Legacy Reprint Series. Due to its age, it may contain
imperfections such as marks, notations, marginalia and flawed
pages. Because we believe this work is culturally important, we
have made it available as part of our commitment to protecting,
preserving, and promoting the world's literature. Kessinger
Publishing is the place to find hundreds of thousands of rare and
hard-to-find books with something of interest for everyone!
In Two Volumes. Illustrated with Ecclesiastical, Historical and
Classical Anecdotes.
In Two Volumes. Illustrated with Ecclesiastical, Historical and
Classical Anecdotes.
John Brady Kiesling, a twenty-year veteran of the foreign service,
publicly resigned his position as political counselor of the U.S.
Embassy in Athens in February 2003 to protest the Bush
administration’s impending invasion of Iraq. He believed that the
security, economic, and moral costs of this war, including the
blackening of America’s image abroad, would far outweigh any
benefit to the American people. In Diplomacy Lessons, Kiesling
reminds readers that U.S. power does not rest on military might
alone and that anger at America has real consequences for U.S.
national interests. The security and prosperity of the American
people depend on efficient cooperation with foreigners on a range
of issues, not only terrorism and nuclear nonproliferation but also
trade policy, environmental protection, and even public health. The
policy decisions of America’s foreign partners are driven by
domestic politics, just as they are in the United States, and
effective U.S. diplomacy requires understanding these political
realities. An unloved superpower faces significant costs, both
economic and strategic, in the pursuit of its interests. Kiesling
calls for a return to realist policy making that recognizes the
limits of U.S. power and uses thoughtful diplomacy to legitimize
our security requirements in the eyes of our international
partners. This book is, at heart, an argument for how to best
achieve America’s goals abroad. Kiesling’s passionate critique
of current U.S. foreign policy and his prescriptions for restoring
American influence and legitimacy will interest anyone concerned
about the future of U.S. and world affairs.
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