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The Handbook of Metabolic Phenotyping (Paperback): John C. Lindon, Jeremy K. Nicholson, Elaine Holmes The Handbook of Metabolic Phenotyping (Paperback)
John C. Lindon, Jeremy K. Nicholson, Elaine Holmes
R5,254 Discovery Miles 52 540 Ships in 10 - 15 working days

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics.

Encyclopedia of Spectroscopy and Spectrometry (Hardcover, 3rd edition): John C. Lindon, George E. Tranter, David Koppenaal Encyclopedia of Spectroscopy and Spectrometry (Hardcover, 3rd edition)
John C. Lindon, George E. Tranter, David Koppenaal
R63,005 Discovery Miles 630 050 Ships in 10 - 15 working days

This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry.

The Handbook of Metabonomics and Metabolomics (Hardcover): John C. Lindon, Jeremy K. Nicholson, Elaine Holmes The Handbook of Metabonomics and Metabolomics (Hardcover)
John C. Lindon, Jeremy K. Nicholson, Elaine Holmes
R5,144 Discovery Miles 51 440 Ships in 10 - 15 working days

Molecular biology operates at three levels - genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level.
The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
* comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies
* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification
* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Metabolic Phenotyping in Personalized and Public Healthcare (Hardcover): Jeremy Nicholson, Ara Darzi, Elaine Holmes, John C.... Metabolic Phenotyping in Personalized and Public Healthcare (Hardcover)
Jeremy Nicholson, Ara Darzi, Elaine Holmes, John C. Lindon
R2,685 Discovery Miles 26 850 Ships in 10 - 15 working days

Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream.

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