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Clinical and preclinical exploration of gene and cellular
immunotherapy have seen rapid growth and interest with the
development and approval of five Chimeric Antigen Receptor T-cell
(CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell
Engager (BiTE) for acute lymphoblastic leukemia (ALL). These
advances have dramatically improved the management of patients with
relapsed refractory lymphoma, myeloma and leukemia. Gene and
Cellular Immunotherapy for Cancer offers readers a comprehensive
review of current cellular and gene-based immunotherapies. Divided
into eighteen cohesive chapters, this book provides an in-depth and
detailed look into cellular-based immunotherapies including CAR-T,
TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers,
focusing on their historical perspectives, biology, development and
manufacturing, toxicities and more. Edited by two leading experts
on gene and cellular immunotherapy, the book will feature chapters
written by a diverse collection of recognized and up-and-coming
experts and researchers in the field, providing oncologists,
immunologists, researchers and clinical and basic science trainees
with a bench to bedside view of the latest developments in the
field.
Clinical and preclinical exploration of gene and cellular
immunotherapy have seen rapid growth and interest with the
development and approval of five Chimeric Antigen Receptor T-cell
(CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell
Engager (BiTE) for acute lymphoblastic leukemia (ALL). These
advances have dramatically improved the management of patients with
relapsed refractory lymphoma, myeloma and leukemia. Gene and
Cellular Immunotherapy for Cancer offers readers a comprehensive
review of current cellular and gene-based immunotherapies. Divided
into eighteen cohesive chapters, this book provides an in-depth and
detailed look into cellular-based immunotherapies including CAR-T,
TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers,
focusing on their historical perspectives, biology, development and
manufacturing, toxicities and more. Edited by two leading experts
on gene and cellular immunotherapy, the book will feature chapters
written by a diverse collection of recognized and up-and-coming
experts and researchers in the field, providing oncologists,
immunologists, researchers and clinical and basic science trainees
with a bench to bedside view of the latest developments in the
field.
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