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Roughly one of every three Americans has some form of
cardiovascular disease (CVD), including more than 70% of persons
older than 75 years of age. Long associated with increased risk for
mortality and disability, CVD is also a major risk factor for
stroke and cerebrovascular disease. There has been growing
consensus that CVD is also an important contributor to poor
neurocognitive outcome in own right. Numerous studies now link CVD
to accelerated cognitive decline, and structural and functional
brain abnormalities, including neurodegnerative conditions in the
elderly. While vascular dementia is the most obvious example of
severe brain dysfunction directly tied to chronic vascular disease,
evidence is also mounting that Alzheimer's disease may be linked to
some of the same pathophysiological mechanisms that underlie
cardiovascular disease. . Controversies in vascular dementia and vascular cognitive
impairment (VCI)
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