This issue of Clinics in Podiatric Medicine and Surgery focuses on Foot and Ankle Arthrodesis. Article topics include: Lesser Toe Arthrodesis; First Metatarsophalangeal Arthrodesis; Tarsometatarsal Arthrodesis for Lisfranc's Injuries;Subtalar Joint Arthrodesis for Elective and Post-Traumatic Foot and Ankle Deformity; Midfoot and Hindfoot Arthrodesis for Elective and Post-Traumatic Foot and Ankle Deformity; Internal and/or External Fixation for Ankle Arthrodesis; Tibiotalocalcaneal Arthrodesis; Management of Osteomyelitis, Bone Loss and Arthrodesis in the Diabetic Charcot Foot and Ankle; Free Flap Coverage for Revisional Foot and Ankle Procedures; and Current Orthobiologics for Elective Arthrodesis and Nonunions of the Foot and Ankle.